摘要
目的比较白内障术中结膜囊内应用5%聚维酮碘与庆大霉素术后眼内炎发生率和不良反应,以评价5%聚维酮碘预防白内障术后眼内炎的有效性、安全性。方法将10659例白内障手术治疗患者分为庆大霉素组和5%聚维酮碘组,术中、术后观察眼部体征并询问患者主观不适。结果2种药物组间眼内炎发病率的差别有显著统计学意义,使用5%聚维酮碘组的眼内炎发病率均较使用庆大霉素组明显降低:ECCE+IOL手术方式由0.29%下降到0.04%;Phaco+IOL手术方式由0.14%下降到0.00%。5%聚维酮碘可引起术中眼部刺激感,但无异物感、刺痛感,无严重并发症。结论术前结膜囊内使用5%聚维酮碘能使白内障术后眼内炎发病率明显下降,且无严重角膜并发症,是一种有效、安全的预防白内障术后眼内炎的措施。
Objective To evaluate the efficiency and the security of 5% povidone-iodine by comparing it with gentamicin on the occurrence of endopbthalmitis after cataract surgery and untoward effects. Methods 10659 cataract patients were divided into the gentamicin group and the 5% povidone-iodine group. All the operative eyes were observed during the sugery and also after it. All the patients were asked to record any malaise. Results There are significant statistical differents between the two drugs, and the morbidity of endophthalmitis of the 5% povidone-iodine group is much lower than the gentamiein group （ decline from 0.29% to 0. 04% of ECCE ＋ IOL and decline from 0. 14% to 0. 00% of Phaco ＋ IOL）. 5% povidone-iodine may cause eye piquant during the surgery, but no foreign body sensation or Prickling sensation. There isn 1 any other complication. Conclusions Topical preoperative 5% povidone-iodine contributed an additional effect to the reduction of the postoperative endophthalmitis rate after cataract surgery. This measure was rather efficiency and safe to apply as a prophylaxis against endophthalmitis in cataract surgery.
出处
《实用医院临床杂志》
2009年第5期76-78,共3页
Practical Journal of Clinical Medicine
关键词
白内障
手术
眼内炎
庆大霉素
聚维酮碘
Cataract
Surgery
Endophthalmitis
Gentamicin
Povidone iodine
