摘要
目的了解临床诊断为艾滋病,而实验室检测HIV抗体不确定样品案例,辅助诊断临床艾滋病病例,弥补抗体检测试剂的局限性,完善现有的艾滋病诊断标准的不足。方法收集2006-2008年四川省内3家医院临床诊断为艾滋病患者而实验室检测HIV抗体呈不确定反应的样本5份,利用病毒载量HIV-1RNA检测技术(EASY-Q),检测样品中病毒载量。结果5份样品,临床诊断艾滋病患者实验室抗体检测出现有膜蛋白抗体(gP160),而确证试验结果为HIV抗体不确定,其病毒载量均在200 000 IU/ML以上。结论结果提示5名临床诊断为艾滋病的患者,其HIV抗体检测不呈阳性反应,但其病毒载量非常高。
Objective To conduct the study on assistant diagnosis of paitients with AIDS clinical symptoms but with uncertain HIV antibodies test results by virus load test Method Five samples with uncertain HIV antibodies test results were collected from 3 grade A hospitals in Sichuan, and the virus load of the samples was detected by Virus Load HIV-1RNA （EASY-Q）. Results The 5 samples that had positive results for membrane antibody （gpl60） and uncertain result for HIV antibody confirmative test had VL （Vires Load） 〉 200 000 IU/mL. Conclusion The result indicated that clinically diagnosed AIDS patient but with uncertian HIV antibody test result mighr have high vius load. Mis-diagnosis could be prevented by comparing with results of other tests, such as DNA detection, taking into account of the epidemiology history of the patient and other factors.
出处
《预防医学情报杂志》
CAS
2009年第8期653-655,共3页
Journal of Preventive Medicine Information
关键词
病毒载量
临床诊断病例
辅助诊断
Viral lord
Clinical AIDS patients
Assistant diagnosis
