摘要
肿瘤干细胞具有高度增殖与自我更新及多向分化的潜能，与肿瘤的复发和难以根治密切相关。在多发性骨髓瘤中亦存在这样一小部分骨髓瘤干细胞，积极探索其起源、免疫分型、信号转导机制、耐药性及其他生物学特性对多发性骨髓瘤的根治有重要意义。
Tumor stem cells have abilities of high proliferation, self-renewal and multi-directional differentiation,which is closely responsible for tumor＇ s survival and recurrence. A minor portion of myeloma stem cells exist in multiple myeloma. The research of myeloma stem cells＇ origins, phenotypic analyses, signaling pathways, drug resistance and other biological characteristics will do great efforts to the effective therapy of multiple myeloma.
出处
《国际肿瘤学杂志》
CAS
2009年第8期629-631,共3页
Journal of International Oncology
