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胃癌基因治疗研究进展

Advancement on gene therapy for gastric cancer
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摘要 胃癌的传统治疗措施效果不理想，近来随着分子生物学及基因工程技术的发展，基因治疗作为肿瘤治疗的新方法逐渐受到人们的重视，胃癌基因治疗研究主要包括以下几个方面：抑癌基因的替代治疗、反义基因治疗、“自杀”基因治疗、免疫基因治疗等。 Gastric cancer is one of the most common tumors. The outcome of conventional therapies is inefficient. In recent years, with development of molecular biology and genetic engineering technology, people pay more attention to gene therapy. The gene therapy for gastric cancer approaches include the following aspects： tumor suppressor gene replacement therapy, antisense gene therapy, ＂suicide＂ gene therapy, immune gene therapy,and so on. This review provides an update of the new developments in cancer gene therapy, new principles, teehniques, strategies and vector systems, and shows how they may be applied in the treatment of gastric cancer.
作者 孙栋(综述) 王西涛(综述) 王新涛(综述) 刘凤军(审校)
机构地区 山东大学齐鲁医院普通外科 河南大学第一附属医院普通外科
出处 《国际肿瘤学杂志》 CAS 2009年第8期611-614,共4页 Journal of International Oncology
关键词 胃肿瘤 基因 肿瘤抑制 癌基因 Stomach neoplasms Genes, tumor suppressor Oncogenes
分类号 R730.5 [医药卫生—肿瘤] R735.2 [医药卫生—肿瘤]
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国际肿瘤学杂志
2009年 第8期

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