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萘丁美酮不良反应的临床观察 被引量:2

Clinical Observation of the Side-effects of Nabumetone
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摘要 目的:临床观察萘丁美酮的不良反应。方法:对200例服用萘丁美酮干混悬剂的门诊患者进行随访,填写《不良反应登记表》,并设100例服用吲哚美辛片为对照组,比较两组不良反应发生率和临床表现。结果:结果萘丁美酮组不良反应发生率为7.5%,主要表现为消化道反应和头晕,耳鸣;对照组不良反应发生率为45%,其主要症状为胃肠不适,且有的较重,患者难以继续用药,两组不良反应发生率差别有显著性意义。结论:萘丁美酮混悬剂不良反应发生率低,服用方便,适合农村患者服用,安全性优于吲哚美辛。 Objective :to observe the side effects of Nabumetone. Methods :to pay follow-up visits to 200 outpatients who have taken Nabumetone, fill out Side Effects Registration Form, and choose 100 patients Who have taken Indomethacin as the control group, then compare the side effects incidence and clinical manifestation of the two groups. Results:side effects incidence of the Nabumetone group is 7.5%, and the main symptoms are gastrointestinal reaction, dizziness, tinnitus; side effects incidence of the control group is 45%, and the main symptoms are severe gastrointestinal discomfort, and patients can hardly take medicine. There is significant difference between the two groups. Conclusion; Nabumetone, with lower side effects incidence and higher security than Indomethacin, is suitable for the patients in the rural area.
作者 罗彪
出处 《安徽卫生职业技术学院学报》 2009年第4期54-54,79,共2页 Journal of Anhui Health Vocational & Technical College
关键词 萘丁美酮 吲哚美辛 不良反应 Nabumetone Indomethacin Side Effects
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