摘要
目的:观察参麦、多巴胺或与多巴酚丁胺、呋塞米及镁剂治疗心衰的疗效。方法:选择各类心脏病伴心衰42例患者随机、双盲、多中心临床试验对比,均给予常规的对症支持等治疗,在此基础上加用多巴胺或与多巴酚丁胺,参麦注射液60mL或25%硫酸镁7~10mL分别加于10%葡萄糖250mL中缓慢滴注。结果:小剂量多巴胺或与多巴酚丁胺、参麦注射液或镁剂治疗心衰,对水肿消退达100%、紫绀缓解率97%。结论:参麦、多巴胺或与多巴酚丁胺、呋塞米及镁剂治疗心衰疗效可靠,且无不良反应,值得临床借鉴探索。
OBJECTIVE To observe the effect of Shenmai, dopamine or dobutamine on chronic heart failure. METHODS The 42 patients with chronic heart failure were chosen in random and double-blinded. After the multi-centre clinical trial constrast and routine treatments, They were injected with dopamine, dobutamine, Shenmai injection 60 mL or 7- ]0 mL 25% magnesium sulfate in 250 mL 10%glucose injection. RESULTS Oedema was faded in all cases (100%) and cyanose allivated in 97% patients treated with small dosage of dopamine or dobutamine, Shenmai injection or magnesium sulfate. CONCLUSION The combination usage with dopamine or dobutamine and Shenmai injection or magnesium sulfate is effective for chronic heart failure without any adverse action.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2009年第16期1381-1383,共3页
Chinese Journal of Hospital Pharmacy