摘要
目的:探讨定君生(乳杆菌活菌制剂)作为阴道假丝酵母菌病(VVC)的辅助治疗及对VVC复发率的影响。方法:将2007年1-12月门诊86例VVC患者,随机分成2组。研究组44例,对照组42例。研究组采用克霉唑阴道片500mg辅以定君生治疗;对照组仅采用克霉唑阴道片500mg治疗。结果:研究组治愈显效率95.45%,对照组90.48%,研究组较对照组治愈显效率高,但差异无显著性(P>0.05);研究组复发率7.14%,对照组复发率16.67%,差异有显著性(P<0.05)。结论:在应用抗假丝酵母菌的药物治疗VVC的同时辅以阴道定植乳杆菌活菌制剂定君生来调整菌群,恢复阴道微生态平衡,可以有效降低VVC的复发率,加强自净作用,增强自然防御功能。
OBJECTIVE To investigate subsidiary treatment about mycobacterium lacticola preparation for vaginal vini candidiasis （VVC） and its recurrence rate. METHODS Divided 86 cases with vaginal vini candidiasis in 2007 into two groups randomly, For 44 cases as test group, with clotrimazole effervescent tablets 500 mg added to mycobacterium lacticola preparation, 42 cases as control group, only with clotrimazole effervescent tablets 500 mg. RESULTS Cure rate of test group was 95.45%, control group was 90. 48%, but differences were not significant （P〉 0. 05） . recurrence rate of test group was 7. 14%, control group was 16. 67%, differences were significant （P〈0. 05） . CONCLUSION Anti-yeast medicine could be used to treat VVC with Mycobacterium lacticola preparation to adjust flora, recover vaginal micro-ecological balance, effectively lower recurrence rate of VVC, strength self-cleaning and improve natural defense.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2009年第16期1377-1379,共3页
Chinese Journal of Hospital Pharmacy
关键词
阴道假丝酵母菌病
乳杆菌
阴道微生态平衡
vaginal vini candidiasis
mycobacterium lacticola
vaginal micro-ecological balance
