摘要
目的调查成年癫痫患者抑郁、焦虑的患病率及可能的危险因素;评价抑郁及焦虑对癫痫患者生活质量的影响。方法采用Beck抑郁问卷(BDI)、贝克焦虑量表(BAI)及癫痫患者生活质量量表-31(QO-LIE-31中文版),对200例成年癫痫患者的抑郁、焦虑情况及生活质量进行评估。结果在200例癫痫患者中43.5%伴发抑郁,28.5%伴发焦虑,23%伴发抑郁及焦虑。发作频繁、无有薪职业是癫痫患者伴发抑郁的重要危险因素,无有薪职业是癫痫患者伴发焦虑的危险因素。抑郁组及抑郁伴焦虑组的QOLIE-31总分及各项评分均低于非抑郁非焦虑组(P=0.000);焦虑组的QOLIE-31总分(P=0.004)及发作的担忧(P=0.019)、认知功能(P=0.009)方面的得分均低于非抑郁非焦虑组。结论抑郁和焦虑是癫痫患者常见的精神共病,严重影响了癫痫患者的生活质量。积极控制发作、为癫痫患者提供更多的就业机会是改善癫痫患者生活质量的重要因素。
Objective To investigate the prevalence of depression or anxiety and the risk factors for them in adult epilepsy patients. To evaluate the effect of depression or anxiety on quality of life in epilepsy patients. Methods We used Beck Depression Inventory,Beck Anxiety Inventory and QOLIE-31 Chinese version to evaluate depression, anxiety and quality of life in 200 epilepsy patients. Results In our study 43.5% patients suffered from depression, 28.5% of them associated with anxiety and 23% patients had both depression and anxiety. Frequent seizures and no paid profession were found to be the risk factors for depression, no paid profession was the risk factor for anxiety . The QOLIE-31 overall score and other suhdomain score of depression group and the depression associated with anxiety group were lower than non-anxiety-depression group （ P = 0. 000）. The QOLIE-31 overall score（ P = O. 004） , seizure worry （ P = 0. 019） and cognitive function domains（ P = 0. 009 ） of anxiety group were lower than non-anxiety-depres- sion group. Conclusion Depression and anxiety are common psychiatric symptoms in epilepsy patients which have seriously affected the patients＇s quality of life . Control of seizures and provide more employment opportunities are im- portant to improve the quality of life of epilepsy patients.
出处
《脑与神经疾病杂志》
2009年第2期123-126,共4页
Journal of Brain and Nervous Diseases
关键词
癫痫
抑郁
焦虑
生活质量
epilepsy
depression
auxiety
quality of life
