摘要
目的:总结甲状腺常见疾病的发病状况、病理学特征及诊断体会。方法:统计分析638例甲状腺冰冻病理及常规石蜡病理活检材料。结果:638例患者中,女:男=2.64:1。结节性甲状腺肿与甲状腺腺瘤的比例为1.5:1。甲状腺癌的高检出年龄段为40～49岁。在冰冻病理诊断中,甲状腺癌的检出率逐年提高,2005年至2008年分别为6.45%、7.58%、14.55%、16.57%。甲状腺乳头状癌是最多见的甲状腺恶性肿瘤,约94.8%,占全部甲状腺疾病的1 1.44%,其中微小乳头状癌占甲状腺乳头状癌的27.40%。多灶性癌占甲状腺癌的15.58%。19.48%的甲状腺癌伴发腺瘤、结节性甲状腺肿及甲状腺炎等良性疾病。甲状腺冰冻病理诊断与石蜡病理诊断定性的符合率为98.59%。钙化在结节性甲状腺肿及甲状腺乳头状癌中较为常见,砂粒体在甲状腺乳头状癌和结节性甲状腺肿两组中具有显著性差异(P<0.01)。结论:乳头状癌是最多见的甲状腺恶性肿瘤,占94.8%,大约1/4为微小乳头状癌。大约1/5的甲状腺乳头状癌伴发腺瘤、结节性甲状腺肿及甲状腺炎等良性疾病。砂粒体在甲状腺乳头状癌诊断中具有非常重要的提示意义。
Objective： To summarize the incidence and the pathological characteristics in frozen sections of thryphaty and the diagnosis of thyropathy. Methods： A total of 638 cases of thyropathy were reviewed using frozen and routine paraffin pathological sections. Results： The female to male ratio was 2.64. The ratio of nodular goiter to thyroid adenoma was 1.5. Most thyroid cancer patients in this study were in the age of 40-49. The detection rate was increased from 2005 to 2008 （6.45%, 7.58%, 14.55%, and 16.57%）. Thyroid papillary carcinoma was the most common thyroid malignant tumor （94.8%） and accounted for 11.44% in thyropathy. Meanwhile, the tiny papillocarcinoma accounted for 27.40% in thyroid papillary carcinoma. The percentage of mulifocal cancer was 15.58% in thyroid cancer. About 19.48% of the patients with thyroid cancer were accompanied with innocent disease, such as adenoma, nodular goiter and thyroiditis. The coincidence of frozen pathologic section and routine paraffin section in diagnosing thyropathy was 98.59%. Calcification was the commom phenomenon in nodular goiter and thyroid papillary carcinoma. There were significant differences in psammoma body between thyroid papillary carcinoma and nodular goiter （P〈0.01）. Conclusion： Thyroid papillary carcinoma is the most common thyroid malignant tumor. A quarter of thyroid papillary carcinomas are tiny papillocarcinoma and 1/5 are accompanied with innocent disease. The psammoma body has an important significance in the diagnosis of thyroid papillary carcinoma.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2009年第15期856-858,共3页
Chinese Journal of Clinical Oncology
关键词
甲状腺疾病
甲状腺癌
钙化
病理分析
Thyropathy
Thyroid carcinoma
Calcification
Pathological analysis
