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难治性抑郁症60例临床特征分析 被引量:4

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摘要 目的探讨难治性抑郁症(TRD)的临床特征。方法收集TRD和非难治性抑郁症(NTRD)各60例。自制问卷调查一般情况及临床特征,用汉密尔顿抑郁量表(HAMD17)评定抑郁症状,测定甲状腺功能,进行统计学分析。结果TRD组发作次数、阳性家族史、残留症状显著多于NTRD组,差异有高度统计学意义(P<0.001)。HAMD17总分两组差异有统计学意义(P<0.05),因子分析TRD组阻滞分显著高于NTRD组,睡眠分显著低于NTRD组,差异均有高度统计学意义(P<0.01)。结论抑郁症阳性家族史、抑郁症残留症状、疾病严重程度、阻滞症状、发作次数多、本次病程长与难治性有关。
出处 《苏州大学学报(医学版)》 CAS 北大核心 2009年第3期554-555,共2页 Suzhou University Journal of Medical Science
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