摘要
目的:肥胖是心房纤颤(房颤)的一个危险因素,但是这种联系的机制还不清楚。本研究旨在评价在窦性心律个体,其体质量指数(BMI)是否是左心房大小的独立决定因素。方法:连续观察18岁以上来我院行经胸超声心动图检查的非心血管病患者180例,均符合窦性心律、左心室收缩功能正常且无瓣膜病及其它心脏病等,记录其年龄、性别,并测量身高及体质量。应用二维及M型超声心动图技术测量左心房大小、左心室功能及左心室后壁厚度(LVPW)。结果:入选者平均年龄(45.54±13.33)岁,体质量指数(24.75±3.65)kg/m2,其中57.2%为男性,BMI是左心房大小的重要预测因子(P<0.001),独立于左心室舒张末内径和左心室后壁厚度。BMI<25 kg/m2者平均左心房面积是(14.16±2.49)cm2,BMI≥25 kg/m2者平均左心房面积是(15.77±2.88)cm2(P<0.001)。结论:在非心血管病者中,肥胖与左心房增大相关,而且独立于左心室大小和左心室后壁厚度。这可能至少部分地有助于解释肥胖人群房颤发生率的增高。
Objective：Obesity is a risk factor for atrial fibrillation （AF） but the mechanisms underlying this association are unclear. We aimed to assess whether body mass index （BMI） is an independent determinant of left atrial size, in subjeects in sinus rhythm. Method： 180 subjects without cardiovascular diseases were consecutive ambulatory patients aged ≥ 18 years who underwent transthoraeic eehocardiography at our hospital. They were confirmed sinus rhythm, nomal LV contractility and no evidence of significant aortic or mitral valve disease and other heart disease et al. At the time of examination,age ,sex,height and weight were measured. Left atrial （LA） area was measured on ultrasound by planimetry. Left ventricular （LV） function and LV posterior wall thickness were measured by M-mode. Result：In these subjects [age （45.54 ± 13.33） years,BMI（24.75 ± 3.65） kg/m^2 , 57.2% male] ,BMI was a significant predictor of LA size （ P 〈 0.001 ） , independent of the significant influences of LV end-diastolic dimension and LV posterior wall thickness. Average LA size was （14.16 ± 2.49） cm^2 in those with normal BMI 〈 25 kg/m^2 , （ 15.77 ± 2.88） cm^2 in obese subjects BMI ≥ 25 kg/m^2 （ P 〈 0.001 ）. Conclusion： Obesity is associated with increased left atrial size in subjects without cardiovascular diseases, independent of the effects of left ventricular size and posterior wall thickness. This may contribute, at least in part, to the rising incidence of atrial fibrillation in the obesity community.
出处
《心肺血管病杂志》
CAS
2009年第4期253-255,共3页
Journal of Cardiovascular and Pulmonary Diseases
关键词
左心房
心房颤动
肥胖
体质量指数
Left atrium
Atrial fibrillation
Obesity
Body mass index
