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可手术的Ⅲ期乳腺癌术前化疗疗效观察

Curative Effects of Preoperative Chemotherapy in the Treatment of Stage Ⅲ Operable Breast Cancer
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摘要 从1981年1月至1991年12月,我们共收治可手术见期乳腺癌61例,其中术前化疗36例,非术前化疗25例。术前化疗组中,经尺动脉插管给药19例,静脉给药17例,有效率分别为73.7%和76.5%(P>0.05),5年生存率分别为68.4%和70.6%(P>0.05),总有效率和5年生率率分别为75.0%和69.4%。5年生存率明显高于非术前化疗组的36.0%(P<0.05)。结果表明:术前化疗对改善可手术Ⅲ期乳腺癌的预后有其重要的意义。 Sixty-one patients with stage Ⅲ operable breast cancer were treated from Jan. 1981to Dec, 1991. All patients were divided into preoperative chemotherapy group (36cases ) and control group (25 cases). In the group of preoperative chemotherapy, nineteen patients were treated by trans-catheter intraarterial infusion, and seventeen patients were treated by venoclysis. The effective rate to preoperative chemotherapy intwo groups was 73. 7 % and 76. 5 % (P>0. 05),respectively. The 5-year survival rate was68. 4% and 70. 6% (P>0. 05),respectively. Total effective rate and 5-year survival rateof the preoperative chemotherapy were 75. 0% and 69. 4%, respectively. The 5-yearsurvival rate was higher than that of control group (36. 0%,P<0. 05). The results indicate that the preoperative chemotherapy on the prognosis of stage Ⅲ operable breastcancer has an important effect.
出处 《肿瘤防治研究》 CAS CSCD 北大核心 1998年第4期291-293,共3页 Cancer Research on Prevention and Treatment
关键词 乳腺癌 术前化疗 生存率 外科手术 Breast cancer Preoperative chemotherapy Five-year survival rate Effective rate Effective rate
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  • 1张斌,中国肿瘤临床,1993年,20卷,462页
  • 2张斌,中华肿瘤杂志,1989年,11卷,228页

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