摘要
目的了解尿路感染病原菌的分布情况及耐药性,为临床医师合理选用抗菌药物提供依据。方法采用常规方法对286株尿路感染病原菌进行菌株鉴定,采用K-B法进行药物敏感试验。结果大肠埃希菌分离率居第1位,62.2%;药敏试验结果显示,尿路感染病原菌对多种抗菌药物均产生了不同程度的耐药性,但革兰阳性球菌对万古霉素、革兰阴性杆菌对亚胺培南敏感率为100.0%;产超广谱β-内酰胺酶(ESBLs)大肠埃希菌和肺炎克雷伯菌检出率分别是36.5%和40.9%;耐甲氧西林葡萄球菌(MRS)平均检出率为35.7%。结论尿路感染病原菌的耐药性已十分严重,应采取有效措施控制耐药菌的流行趋势。
OBJECTIVE To investigate distribution status and drug-resistance pathogens from infected urinary tract and offer scientific evidence for reasonably clinical usage of antibiotics. METHODS A total of 286 strains of pathogenic bacteria isolated from urinary tract were identified by common methods. Antibiotic susceptibility tests were performed by K-B methods. RESULTS Escherichia coli rated the top one, accounting for 62.2%. Results of susceptibility test showed that all pathogens were resistant to the many antibiotics in different degrees except for 100.0% sensitive to vancomycin in Gram-positive cocci and to imipenem in Gram-negative bacilli. The detection rate of extensive-spectrum beta-lactamases （ESBLs） producers in E. coli and Klebsiella pneumoniae was 36.5 % and 40. 9%, respectively. The average detection rate of meticillin-resistant staphylococci （MRS） was 35. 7%. CONCLUSIONS The drug-resistance of pathogenic bacteria from infected urinary tract is quite serious in the local area. We should adopt effective measurement to control its prevalence.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2009年第16期2203-2205,共3页
Chinese Journal of Nosocomiology
关键词
尿路感染
病原菌
分布
耐药性
Urinary tract infection
Pathogens
Distribution
Drug-resistance
