摘要
为了研究血清中CEA（癌胚抗原）、CA15－3与化疗疗效的关系，为癌症病人正确选择化疗方案，对54例乳腺癌根治术后病人在化疗前、化疗后每周取外周血测定血清中CEA、CA15－3，并将其与未做这样的血清CEA、CA15－3测定的30例乳腺癌根治术后的化疗病进行对比。结果表明：化疗过程中血清CEA、CA15－3的浓度与肿瘤细胞对化疗药物的敏感性有明显的相关性。化疗过程中血清CEA、CA15－3浓度下降，标志化疗有效；若血清CEA、CA15－3浓度不呈下降趋势，则应更改化疗方案，至血清CEA、CA15－3呈下降趋势为上。
The paper is to study the relation of the serum CEA and CA15 - 3 with chemotherapeutical effect, and to guide to choice correct chemotherapeutical scheme. Serum CEA and CA15 - 3 in 54 patients after radical operation of mammary cancer were determined before chemotheraopy and every week after chemotherapy, which were compared with nondetermined CEA and CA15 - 3 groups. It was discovered that the levels of CEA and CA15 - 3 had relation with the sensitivity of chemotherapeutic chemicals to tumor cells. During chemotherapy, chemotherapy was effective, when serum CEA and CA15 - 3 levels reduced markedly. If serum levels of CEA and CA15 - 3 were not declined, chemotherapy scheme should be changed so as to reduce CEA and CA15 - 3 levels. Thus, recurrence and transfer become possibly lower and survival rate is raised
出处
《标记免疫分析与临床》
CAS
1998年第2期84-86,共3页
Labeled Immunoassays and Clinical Medicine
