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丝裂霉素C在治疗难治性青光眼的临床应用 被引量:2

Clinical Application of Mitomycin C for Refractory Glaucoma
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摘要 目的观察小梁切除术中联合丝裂霉素C(MMC)治疗难治性青光眼的疗效。方法小梁切除术中联合丝裂霉素C治疗18例18眼难治性青光眼,术后随访1年,观察其临床疗效及手术并发症。结果手术成功率为83.3%;眼压由术前的(45.17±12.01)mmHg降至术后的(16.89±3.42)mmHg。采用配对t检验差异有统计学意义(P<0.01)。术后并发症为滤过泡漏,前房出血,浅前房。结论小梁切除术联合丝裂霉素C手术治疗难治性青光眼是一种相对安全有效的治疗方法。 Objective To observe the therapeutic effects of trabeculectomy combined with mitomycin C on the refractory glaucoma. Methods A study of clinical effect and complications were conducted on 18 eyes from 18 patients with refractory glaucoma with oneyear follow-up.Results The success rate of surgery was 83.3% .The average IOP decreased from the preoperative(45.17± 12.01) mmHg to the postoperative( 16.89±3.42)mmHg(P〈0.01 ) .The complications included filtering bleb leakage, hyphema,flat anterior chamber.Conclusion trabeculectomy combined with mitomycin C may be effective and safe for treating refractory glaucoma.
出处 《中外医疗》 2009年第23期183-184,共2页 China & Foreign Medical Treatment
关键词 丝裂霉素C 难治性青光眼 小梁切除术 Refractory glaucoma Trabeculectomy Mitomycin C
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参考文献8

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  • 2Chen CW. Trabeculectomy with simul traneous topical application of mitomycin C refractory glaucoma[J].J OcularPharmacol, 1990,6 : 175 - 176.
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  • 4傅少颖,刘红玲,侯勇生,金迪,崔浩.改良青光眼滤过手术在难治性青光眼中的应用[J].中国实用眼科杂志,2003,21(12):942-943. 被引量:10
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