期刊文献+

急性心肌梗死患者胆红素和血脂水平临床研究

暂未订购
导出
摘要 目的:探讨血脂蛋白和胆红素在急性心肌梗死中的作用。方法:36例急性心肌梗死患者采用酶法测定胆固醇(TC)、甘油三脂(TG),采用直接法测定高密度脂蛋白(HDLC)、低密度脂蛋白(LDLC),采用钒酸盐氧化法测定总胆红素(TB)和直接胆红素(DB)水平。结果:急性心肌梗死组的TG、LDLC较对照组显著增高(P<0.05),总胆红素及直接胆红素较对照组显著降低(P<0.05)。结论:高胆固醇、高密度脂蛋白是导致急性心肌梗死的主要脂类危险因素。胆红素低的患者患急性心肌梗死的危险性增加,证明胆红素对冠状动脉具有保护作用。
作者 徐庆员
出处 《中国社区医师(医学专业)》 2009年第15期13-13,共1页
  • 相关文献

参考文献3

二级参考文献21

  • 1Hunt SC,Kronenberg F,John H,et al.Association of plasma bilirubin with coronary heart disease and segregation of bilirubin as a major gene trait:the NHLBI family heart study[J].Atherosclerosis,2001,154(3): 747-754.
  • 2Ishikawa K,Navab M,Leitinger N,et al.Induction of heme oxygenase-1 inhibits the monocyte transmigration induced by mildly oxidized LDL[J].J Clin Invest,1997,100(5):1209-1216.
  • 3Hunt SC,Wu LL,Hopkins PN,et al.Evidence for a major gene elevating serum bilirubin concentration in Utah pedigrees[J].Arterioscler Thromb Vasc Biol,1996,16(8):912-917.
  • 4Wu TW,Fung KP,Wu J,et al.Antioxidation of human low density lipoprotein by unconjugated and conjugated bilirubins[J].Biochem Pharmacol,1996,51(6):859-862.
  • 5Levinson SS.Relationship between bilirubin,apolipoprotein B and coronary artery disease[J].Am Clin Lab Sci,1997,27(3):185-192.
  • 6Kronenberg F,Coon H,Gutin A,et al.A genome scan for loci influencing anti-atherogenic serum bilirubin levels[J].Eur J Hum Genet,2002,10(9):539-546.
  • 7Lin JP,Cupples LA,Wilson PWF,et al.Evidence for a gene influencing serum bilirubin on chromosome 2q telomere: a genomewide scan in the Framingham study[J].Am J Hum Genet,2003,72(4):1029-1034.
  • 8Mietus-Snyder M,Friera A,Glass CK,et al.Regulation of scavenger receptor expression in smooth muscle cells by protein kinase C:a role for oxidative stress[J].Arterioscler Thromb Vasc Biol,1997,17:967-978.
  • 9Wu TW,Wu J,Li RK,et al.Albumin-bound bilirubins protect human ventricular myocytes against oxyradical damage[J].Biochem Cell Biol,1991,69:683-688.
  • 10Hopkins PN,Wu LL,Hunt SC,et al.Higher serum bilirubin is associated with decreased risk for early familial coronary artery disease[J].Arterioscler Thromb Vasc Biol,1996,16(2):250-255.

共引文献100

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部