摘要
炎症是动脉粥样硬化(atheroscle rosis,AS)疾病关键的病理环节之一。AS发病相关的多个危险因素均与炎症信号调节密切相关。深入研究AS炎症信号通路,并研制有效的干预药物,可能成为影响AS炎症反应乃至AS病变过程的有效途径。
Inflammation is one of the key pathological process of atherosclerosis(AS),and multiple risk factors of AS have con-sanguineous relationships with the regulation of inflammatory signal pathway.So it could be effective approach to control inflammation,even the pathological process of AS if we do the deep research on AS inflammatory signal pathway and make out the potential medicine.
作者
李玉洁
杨庆
翁小刚
王怡薇
朱晓新
LI Yu-jie;YANG Qing;WENG Xiao-gang;WANG Yi-wei;ZHU Xiao-xin(Institute of Chinese Materia Medica,China Academy of TCM Science,Beijing 100700,China)
出处
《中国药理学通报》
CAS
CSCD
北大核心
2009年第7期857-860,共4页
Chinese Pharmacological Bulletin
基金
国家科研院所技术开发研究专项资助(NoNCSTE-2007-JKZX-301)
中国中医科学院基本科研业务费自主选题项目
关键词
动脉粥样硬化
炎症
信号转导
atherosclerosis
inflammation
signal pathway