摘要
目的评估不同浓度酚妥拉明治疗毛细支气管炎的疗效。方法将171例毛细支气管炎住院患儿随机分为4组,,即A、B、C三治疗组及对照组D组。4组均患儿均采用常规治疗,治疗组在上述治疗基础上加用酚妥拉明,依次分别给予酚妥拉明浓度为1-1.5μg/(kg·min)、1.5-2μg/(kg·min)、2-3μg/(kg·min),比较4组患儿疗效及不良反应发生情况。结果总有效率A、B治疗组与对照组差异显著,A、B两治疗组间差异不显著;不良反应发生率各治疗组差异显著。结论①酚妥拉明治疗毛细支气管炎的疗效显著②酚妥拉明治疗毛细支气管炎最适浓度为1μg/(kg·min)。
Objective It is to observe the therapeutic effect on bronchioliti by different density of phentolamine. Methods 171 infantile patients of bronchioliti are randomly divided into three treated groups （A,B,C groups） and one contrast group. All infants are treated with antiviral drugs, redehydration, smecta, supportive treatment and Lactose-free Formula. On the basis of combined therapy, A,B,C groups are given by taking different density of the application of phentolamine（1-1.51μg/kg·min, 1.5-21μg/kg·min、2-31μg/kg·min）. Comparison of these four groups in bronchiolit and three treated groups in adverse effect. Results There is significant difference between therapeuti Group and contrast groups in bronchioliti total effective rate. But there aren＇t predominant differences between A group and B group. In adverse effect rate, A,B,Cgroups are predominant differences. Conclusion （1） Taking phentolamine is an effective method to treat bronchioliti. （2） The author thinks that the optimum density is 1-1.5μg/（kg·min）.
出处
《中国现代药物应用》
2009年第15期26-28,共3页
Chinese Journal of Modern Drug Application
