摘要
目的:探讨病毒性肝炎对骨髓造血功能的影响。方法:检测肝功能、免疫学、血液学、骨髓象或活检,对27例肝炎伴骨髓抑制患者,其中17例再障(AA),10例纯红再障(PRCA)进行临床分析。结果:27例住院患者中急性肝炎12例,慢性肝炎8例,淤胆型3例,重症型肝炎4例。骨髓抑制属急性21例、慢性6例。病毒检测示 HAV IgM:AA13/13例(-),PRCA5/10例(+)。HBVM:AA7/17例(+),PRCA3/10例(+)。骨髓抑制出现时,临床可表现为发热、贫血、出血。结论:病毒性肝为可引起骨髓功能的抑制,应早期诊断,及时治疗。
Objectives:To explore the relationship between viral hepatitis and bone marow function.Methods:27 cases of hepatitis with bone marrow depression diagnosed by liver function,immunologic and hematologic changes,mar- row smear and/or biopsy were analysed.17 cases were aplastic anemia(AA).10 were pure red cell aplasia(PRCA). Results:27 cases of hepatitis associated with bone marrow depression were admitted in this hospital among a total of 55935 cases of hepatitis.12 were acute hepatitis,8 chronic hepatitis,3 intrahepatic cholestasis and 4 severe viral hepati- tis.Among these,21 were acute marrow depression,6 were chronic.Serologic tests showed negative anti-HAV IgM in all 13 cases of AA,5 positive in 10 cases of PRCA and HBVM positive in 7/17 of AA.3/10 in PRCA.The symptoms onset were fever,anemia and bleeding.Conclusion:As viral hepatitis can cause depression of bone marrow,it shouldbe diagnosed and treated timely and properly.
出处
《上海医学》
CAS
CSCD
北大核心
1998年第7期387-388,共2页
Shanghai Medical Journal
关键词
病毒性肝炎
贫血
骨髓功能
抑制
Viral hepatitis
Aplastie anemia
Pure red cell aplasia
