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PCR鉴定HBsAg阴性肝炎中HBVDNA的临床意义探讨 被引量:1

Approach to the Significance of Determining HBVDNA in HBsAg Negative Patients With PCR
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摘要 收集HBsAg阴性HBcAb阳性慢性乙肝病人血清30例,恢复期急性乙肝病人血清100例,用PCR技术检测HBVDNA,结果检出率分别为70%和28%,说明上述某些病例虽然HBV用一般方法不易检出,但HBVDNA复制并未停止,其血清仍具有传染性。还证实随年龄增长,HBV感染者病变恢复较慢。 Serum was collected from 30 patients of HBsAg negative and HBcAb positive chronic hepatitis B and from 100 patients of restoration stage with acute hepatitis B. HBV DNA was detected with PCR and the results showed positive rates of 70% and 28% respectively, which indicated that though in some cases, HBV could not be easily detected, the replication of HBV DNA did not stop and the serum was still contagious. It has been proved that with the increase of one's age, the recovery of HBV patient was slow. The authors believe that trace study of the above patients with PCR technique is quite necessary.
作者 李星 秦瑛
出处 《预防医学情报杂志》 CAS 1998年第3期149-150,共2页 Journal of Preventive Medicine Information
关键词 乙型肝炎 HBVDNA 表面抗原 阴性 聚合酶链反应 chronic hepatitis B restoration stage of acute hepatitis B HBV DNA PCR
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