摘要
目的对经皮穿刺注射医用臭氧联合胶原酶治疗腰椎间盘突出症的中期疗效观察。方法78例经影像学及临床检查证实腰椎间盘突出症患者,CT引导下行经皮穿刺椎间盘内注入医用臭氧,2～4d后再经硬膜前间隙在突出物表面及突出物内注入医用胶原酶1200u行髓核溶解术。结果术后6～25个月随访观察,78例中疗效优58例(74.3%),良16例(20.5%),差4例(5.1%)。12例术后2个月内出现症状复发,其中9例2个月后自行好转,3例经再次注射臭氧后,症状消失。无严重并发症,经治疗后症状消失者随访未见复发。结论经皮穿刺行医用臭氧联合胶原酶治疗腰椎间盘突出症,两者优势互补,可以提高疗效,是一种安全、微创、有效的治疗方法。
Objective To observe the mid-term effectiveness of percutaneous lumbar puncture and injection of medical ozone and collagenase in treating lumbar disc herniation. Methods CT-guided percutaneous lumbar puncture and medical ozone injection into the intervertebral disc was performed in 78 patients with lumbar disc herniation, which was confirmed by imaging study or clinical manifestations. After 2 - 4 days, neucleolysis was carried out. Collagenase 12 000 U was injected via the anterior epidural space onto the surface or into the inside of the prominence of the protruded disc. Results The clinical results were evaluated in 6 - 25 months after the procedure. Of 78 patients treated with this technique, the result was excellent in 58 （74.3%）, good in 16 （20.5%） and poor in 4 （5.1%）. Symptoms returned in 12 cases in 2 months after the procedure, and the reappeared symptoms were relieved in 9 of them within 2 months without giving any treatment. In 3 cases the symptoms disappeared after repeated injection of medical ozone. No serious complications occurred. Conclusion Percutaneous lumbar puncture and injection of medical ozone combined with collagenase is an effective, safe and minimally-invasive therapy for lumbar disc herniation.
出处
《介入放射学杂志》
CSCD
北大核心
2009年第7期515-517,共3页
Journal of Interventional Radiology
关键词
医用臭氧
胶原酶髓核溶解术
腰椎间盘突出症
medical ozone
collagenase
nucleolysis
lumbar intervertebral disc protrusion
