摘要
以3-芳基-5-巯基-1,2,4-三唑为原料,在酸性条件下与乙酰丙酮和乙酰乙酸乙酯一步成环,制备得到12种新的2-芳基-5-取代-6-甲基噻唑并[3,2-b](1,2,4)-三唑类衍生物.所有化合物结构经IR,1HNMR,13CNMR和MS及元素分析确证。
Twelve novel compounds, 5-（substituted phenyl）-2-substituent-3-methylthiazolo[3,2-b]（1,2,4）- triazole derivatives, were synthesized by a one-pot reaction of 3-（substituted phenyl）-4,5-dihydro-l,2,4- triazole-5-thiones with acetylacetone or acetylacetic ester in the presence of acid. The structures of the compounds were confirmed by IR, ^1H NMR, ^13C NMR, MS techniques and elemental analysis.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2009年第7期1133-1137,共5页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(No.20771059)
江苏省高校自然科学基金(No.05KJB-150039)资助项目
