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颅内恶性肿瘤再手术的探讨

Discussion of reoperation for encephalic malignancy
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摘要 目的探讨颅内恶性肿瘤再手术的适应证及意义。方法回顾性分析我院52例颅内恶性肿瘤再手术病例。其中多形性胶质母细胞瘤(GBM)9例,星形细胞瘤34例,间变性脑膜瘤3例。结果再手术后平均存活期为50.2周,术后1个月80%患者KR较术前有明显改善。术中全切肿瘤的病人较次全切肿瘤的病人生存期延长(P<0.0001)。结论术前卡氏分级KR≥60,第一次术后病例为星形细胞瘤Ⅰ~Ⅲ级,两次手术间隔>6个月,全身情况稳定,应积极再手术。 Objective To discuss the indications and significance of encephalic malignancy reoperation. Methods Fifth-two cases of encephalic malignancy reoperation in our hospital were retrospectively analyzed, including 9 cases of pleomorphic spon- gioblast tumor, 34 cases of astrocytoma and 3 cases of anaplasia meningoma. Results Average survival phase after reoperation was 50. 2 weeks. Eighty percent of the patients had KR obviously ameliorated 1 month after reoperation. Patients of total excision during reoperation had longer survival phase than those of subtotal excision (P〈0. 0001). Conclusion If a patient with KR ≥60 before opertaion indicates level Ⅰ to Ⅲ astrocytoma after first time operation, interval of two operations is longer than 6 months, and the body is stable, reoperation should be applied.
作者 曾彪
出处 《中国实用神经疾病杂志》 2009年第12期23-25,共3页 Chinese Journal of Practical Nervous Diseases
关键词 颅内肿瘤 再手术 Intracranial tumors Reoperation
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参考文献3

  • 1Ray BR.Surgery of recurrent infracranial tumors[J].Clin Neurosurg,1984,10:30.
  • 2Young B,Oldfield EH,Markesbery WR,et al.Reoperation for glioblastoma[J].J Neurosurg,1981,55:917.
  • 3徐温理.复发性脑胶质瘤的再手术.中华外科杂志,2004,29:768-768.

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