期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

不同空腹血糖水平血清白介素18与白介素6含量及相关因素分析 被引量：6

The serum interleukin-18 and interleukin-6 concentration and their associated factors under different fasting plasma glucose
原文传递
导出
摘要 分析不同FPG状态下血清白介素18(IL-18)、IL-6含量及相关因素,发现不同FPG水平下血清IL-18水平有明显不同(P<0.01),且随FPG升高而升高;血清IL-6水平在FPG≥6.1mmol/L时显著增高(P<0.01,P<0.05)。推测IL-18可能是导致2型糖尿病发生的重要细胞因子之一。 We analyzed the relationship of FPG with the concentration of IL-18 and IL-6 in the situation of different fasting plasma glucose. The serum IL-18 levels were significantly different among all groups（P〈0. 01）. With FPG increasing, the IL-18 levels were increased. The serum IL-6 levels were higher in the subjects with FPG≥6. lmmol/L （P〈0. 05）. IL-18 might be an important molecule for advancing type 2 diabetes.
作者 谢晓敏 牛旭东 李仁达 于丽萍 周海燕 张丽 刘惠莉 李玲 曾斌 史静
机构地区 宁夏医学院第二附属医院银川市第一人民医院内分泌科
出处 《中国糖尿病杂志》 CAS CSCD 北大核心 2009年第7期539-540,共2页 Chinese Journal of Diabetes
基金 宁夏银川市科技攻关基金资助项目(06-1-60)
关键词 空腹血糖 白介素18 白介素6 Fasting plasma glucose Interleukin-18 Interleukin-6
分类号 R587.1 [医药卫生—内分泌]
  • 相关文献

参考文献7

  • 1Esposito K,Nappo F,Marfella R,et al.Inflammation cytokine concentrations are acutely increased by hyperglycemia in human: role of oxidative stress[].Circulation.2002
  • 2Nakamura A,Shikata K,Hiramatsu M,et al.Serum interleukin-18 levels are associated with nephropathy and atherosclerosis in Japanese patients with type 2 diabetes[].Diabetes Care.2005
  • 3Esposito,K,Marfella,R,Giugliano,D.Plasma interleukin-18 concentrations are elevated in type 2 diabetes[].Diabetes Care.2004
  • 4Esposito K,Ciotola M,Carleo D, et a1.Effect of rosiglitazone on endothelial function and inflammatory markers in patients with the metabolic syndrome[].Diabetes Care.2006
  • 5A. Zirlik,S.M. Abdullah,N. Gerdes.Interleukin-18, the metabolic syndrome, and subclinical atherosclerosis: results from the Dallas Heart Study[].Arteriosclerosis and Thrombosis.2007
  • 6Olusi SO,AI-Awadhi A,Abraham M.Relations of serum interleukin 18 levels to serum lipid and glucose concentrations in an apparently healthy adult population[].Hormone Research.2003
  • 7MARFELLA R,ESPOSITO K,SINISCALCHI M,et al.Effect of Weight Loss on Cardiac Synchronization and Proinflammatory Cytokines in Premenopausal Obese Women[].Diabetes Care.2004

同被引文献32

  • 1王瑶,杨文英,杨兆军,李光伟.从心血管危险因素看空腹血糖受损切点下调[J].中华内分泌代谢杂志,2004,20(5):399-402. 被引量：25
  • 2贾海燕,田浩明.糖苷酶抑制剂治疗糖耐量减低的循证医学研究与评价[J].中国实用内科杂志,2005,25(4):296-298. 被引量：23
  • 3潘孝仁,李光伟,胡英华,王继兴,杨文英,安作新,刘娟,曹辉碧,胡泽溪,庞成言,张辉,郑辉,王金平,姜希贵,姜亚云.饮食和运动干预治疗对糖尿病发病率的影响──530例糖耐量低减人群六年前瞻性观察[J].中华内科杂志,1995,34(2):108-112. 被引量：243
  • 4俞匀,朱大龙,徐小华,胡云,沈山梅,黄群.2型糖尿病患者一级亲属脂联素及三种细胞因子与胰岛素抵抗的相关性[J].中国糖尿病杂志,2006,14(4):247-249. 被引量：10
  • 5Gerstin HC,Santaguida P,Raina P,et al.Annual incidence and relative risk of diabetes in people with various categories of dysglycemia:a systematic overview and meta-analysis of prospective studies[J].Diabetes Res Clin Pract,2007,78(4):305-312.
  • 6Knowler WC,Barrett-Connor E,Fowler SE,et al.Reduction in the evidence of type 2 diabetes with life-tyle intervention or metformin[J].N Engl J Med,2002,346(6):393-403.
  • 7Bojestig M, Arnqvist HJ, Hermansson G, et al. Declining incidence of nephropathy in insulin -dependent diabetes mellitus[ J]. N Engl J Med,1994,330:15 - 18.
  • 8Krolewski AS, Warram JH, Rand LI, et al. Epidemiologic approach to the etiology of type I diabetes meUitus and its complications [ J ]. N Engl J Med,1987 ,317 :1390 -1398.
  • 9Kerrin S Small,Asa K Hedman. Identification of an imprinted mas- ter trans regulator at the KLF14 locus related to muhiple metabolic phenotypes [ J ]. Nature Genetics Volum Number June, 2011,43 (6) :561 -564.
  • 10Nicklas B J, Wang X, You T, et al. Effect of exercise intensity on ab- dominal fat loss during calorie restriction in overweight and obese postmenopausal women : a randomized, controlled trial [ J ]. Am J Clin Nutr,2009,89(4) :1043 - 1052.

引证文献6

二级引证文献6

中国糖尿病杂志
2009年 第7期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部