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前列地尔与西洛他唑联用治疗老年下肢动脉硬化闭塞症 被引量:18

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摘要 目的观察前列地尔与西洛他唑(Cilostazol,CS)联用治疗老年下肢动脉硬化闭塞症的疗效。方法老年下肢动脉硬化闭塞症患者68例,随机分为用前列地尔组与联用西洛他唑组,比较两组治疗前后主观症状、血管踝臂指数(ABI)、最大行走距离和足背动脉血流量的变化。结果前列地尔组与联用西洛他唑组间歇性跛行、疼痛感及麻木感治疗后较治疗前均有明显改善,两组总有效率比较无统计学意义,但显效率比较西洛他唑组明显高于前列地尔组(P<0.05),在冷感改善方面联用西洛他唑组明显好于前列地尔组(P<0.01)。两组最大行走距离、ABI、足背动脉血流量均较治疗前有明显改善(P<0.05),且最大行走距离、足背动脉血流量联用西洛他唑组增加更明显(P<0.05)。结论前列地尔与西洛他唑联用治疗老年下肢动脉硬化闭塞症安全有效。
出处 《中西医结合心脑血管病杂志》 2009年第7期862-863,共2页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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  • 1畅坚,许樟荣,王志强,陈平,杨丽娜.糖尿病与非糖尿病患者外周动脉病变血管造影对比研究[J].中华糖尿病杂志(1006-6187),2004,12(5):324-327. 被引量:75
  • 2[1]Ouriel K. Peripheral artery disease. Lancet , 2001, 358 :1257-1264.
  • 3[3]Diabeted drafting group. Prevalence of small and large vessel disease in diabetic patients from 14 centers. The WTO multinational study of vascular disease in diabetics. Diabetologia,1985,28(Suppl): 615-640.
  • 4[4]Jude EB, Chalmers NC, Oyibo SO, et al. Peripheral arterial disease in diabetic and nondiabetic patients - a comparison of severity and outcome. Diabetes Care, 2001,24:1433-1437.
  • 5[7]Toyata T,Hirata Y. Lipo-PGE1 ,a new lipidencapsulated preparation of prostaglandin E1 placebo and prostaglandin E1-eontrolled multi center trials in patients with diabetic neuropathy and leg ulcers. Prostaglandins, 1993,46:453.
  • 6[8]Makino H, Aoki M, Hashiya N, et al. Increase in peripheral blood flow by intravenous administration of prostaglandin E1 in patients with peripheral arterial disease, accompanied by upregulation of hepatocyte growth factor. Hypertens Res, 2004,27:85-91.
  • 7[9]Mlekusch W, Schillinger M, Sabeti S, et al. Effects of intravenous prostaglandin E1 on arterial compliance: a randomized controlled trial. Vasa,2004, 33:131-136.
  • 8Premalatha G,Shanthirani S,Deepa R, et al. Prevalence and risk factors of peripheral vascular disease in a selected South Indian population: the Chennai Urban Population Study [J]. Diabetes Care, 2000,23 : 1295-3000.
  • 9Fowkes FGR. Epidemiology of peripheral vascular disease[J]. Atherosclerosis, 1997,131 (Suppl) : S29-S31.
  • 10Dormandy J, Mahir M, Ascady G, et al. Fate of the patient with chronic leg ischaemia[J]. J Cardiovasc Surg, 1989,30:50-57.

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