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65岁以上老年患者口服华法林抗凝的安全性探讨 被引量:18

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摘要 目的探讨65岁以上老年患者口服华法林抗凝治疗的安全性。方法对2003年1月—2007年11月具有华法林抗凝适应证的65岁以上住院患者进行回顾性分析,并进行随访。结果①201例具有华法林抗凝适应证的患者,服用华法林98例,其中发生出血并发症14例(14.3%),患者出血时国际标准化比值(INR)>3.0者8例(57.1%)。在INR<2.0的出血患者中75%合并有出血潜在的基础疾病或合并用影响华法林抗凝作用的药物。②201例患者中非瓣膜病心房颤动患者98例,其中具有华法林抗凝指征并接受抗凝治疗者42例(42.86%)。结论65岁以上具有华法林抗凝适应证的老年患者口服华法林时,应密切监测有无出血并发症发生。
作者 耿强 郭丹杰
出处 《中西医结合心脑血管病杂志》 2009年第7期834-835,共2页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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