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氯诺昔康超前镇痛在子宫次全切除手术中的应用

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摘要 目的:观察氯诺昔康超前镇痛对子宫次全切除术后患者镇痛效果的影响。方法:60例子宫肌瘤患者于硬膜外麻醉下行经腹子宫次全切除术。随机分为超前镇痛组(A),于手术切皮前30min静脉缓慢推注氯诺昔康16mg;预防性镇痛组(B),于手术结束关腹时静脉缓慢推注氯诺昔康16mg;对照组(C)不做任何处理。术后不同时间点观察视觉模拟评分(VAS),应用镇痛药情况及不良反应。结果:A组与B组均能在术后12h内产生良好的镇痛效果,且A组在术后2、4、12hVAS评分显著低于B组(P<0.05)。A组术后第一次应用镇痛剂的时间较C组明显延长,且未增加术后不良反应的发生率。结论:氯诺昔康行超前镇痛可有效缓解子宫次全切除术后患者腹部疼痛,提高舒适度,抑制患者术后的不良反应。
出处 《吉林医学》 CAS 2009年第13期1321-1322,共2页 Jilin Medical Journal
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参考文献4

  • 1Cliff RS,Ong DS,Philipp L,et al.The efficacy of preemptive analgesia for acture postoperative pain management:A meta-analysis[J].Anesthanalg,2005,100(5):757.
  • 2Sinatra R.Role of Cox-2 inhibitors in the evolution of acute pain management[J].Pain and Sympotom Management,2002,24:s18.
  • 3杨经文,谭玲.氯诺昔康的药理及临床应用[J].华西医学,2004,19(4):686-687. 被引量:20
  • 4Norholt SE,Sindet-Pedersen S,Bugge C,et al.A randomized double-controlled,does-response study of the analgesic effect of lornoxican after surgical removal of mandibular third molars[J].J Clin Pharmacol,1995,35(6):606.

二级参考文献16

  • 1[1]Berg J,Christoph T,Fellier H.Theanalqesic NSAID Lornoxicam inbibirs cox-1/cox-2,iNOs and the formation of IL-6 in vitro[J].Nannyn-Schmiod Arch pharmacol,1998,358(suppl.2):R716.
  • 2[2]Berg J,christoph T,Widerna M,Bodenteich A.Isoenzyme-Specific Cyclooxygenase inhibitirs:A whole cen assay ayatem using the human erythrolukemic cenrl line HEL and the human monocytic ceril line monomai6[J].J pharmacol Toxicaol meth,1997,37:179-86.
  • 3[3]Turner P,Johnston-A.clinical pharmacokinetic studies with lornoxicam[J].Postgracl Med J,1996(suppl.4):28.
  • 4[4]Pruss T P,stroissing H,Radhifer WS,et al.overview of the pharmacological properties,pharmacokhetics and animal gafety assessment of lornoxicam[J].Postgrad Med J,1990,66(suppl.4):28.
  • 5[5]Staunstrup H,Ovesen UY,Elbaek KJ,Larsen U,Kroner K.Efficacy and tolerability of lornoxicam versus tramadol in postoperative pain[J].J xlin Pharmacol,1999,39(8):834-41.
  • 6[6]Norholt SE,sindet-pedersen S,Larsen U,et al.Pain control after dental surgery:a double blind,randomized trial of lornoxic am versus morphine pain,1996,Oct;67(2-3):335-43.
  • 7[7]Norholt SE,Sindet-pedersen S,Buqqe C,et al.A randomized,double-blind,placdbo controlled,dose-response study of the analpesic effect of lomoxicam after surqical removal of mandibular third molars[J].T slin oharmacol,1995,35(6):606-14.
  • 8[8]Rosenow DE,van krieken F,stolke D,et al.Intruvenous adminsrrstion of lomxicam,a new NSAID,and pethidme for postoperation pain[J].Clin Drug znvest,1996,11(1):11.
  • 9楼红英.氯诺昔康在人流术中的应用[J].南京部队医药,2001,20(3):251-252.
  • 10[11]Kidd B,Frenzel W.A multi certer,randomived,double blind study comparing lomoxicam with dislofenal in osteoarthritis[J].J Rheumatol,1996,23(9):1650-11.

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