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辽宁地区汉族人群克罗恩病的疾病行为分析 被引量:3

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摘要 目的研究辽宁地区中国人群克罗恩病(CD)的疾病行为。方法回顾性分析1965年-2007年185例住院CD患者的临床表现、影像学特点、病理及手术所见,并采用蒙特利尔分型。结果185例CD患者以17~40岁为发病高峰(53.0%)。CD病变部位以回结肠(L3)最为多见,占43.8%,其次为结肠(L2)和末端回肠(L1),单独发生于上消化道(L4)的仅2例。CD疾病行为以狭窄型(B2)最常见,占47.0%,穿透型发病率较国内外报道为高,其中肠穿孔19例,穿壁性炎症7例,内外瘘管22例。185例患者共进行104次手术,术中所见显示肠壁增厚严重,有的呈肿块样堵塞肠腔。在增殖性病变的肠段上可见大小、形态各异的溃疡和穿孔,肠管与腹膜或邻近脏器常有粘连,形成团块这些均能加深对CD疾病行为的了解。结论辽宁地区CD的疾病行为大多以B2、B3合并症的形式出现,尤其穿透型发病率高。因此临床上应结合症状、内镜、CT等综合判断,才能得出正确诊断。
出处 《中华消化杂志》 CAS CSCD 北大核心 2009年第6期411-414,共4页 Chinese Journal of Digestion
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