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初探血清白介素-13在COPD不同时期的变化 被引量:4

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摘要 目的临床观察慢性阻塞性肺疾病患者血清白介素-13水平,探讨慢性阻塞性肺疾病对血清白介素-13的影响。方法入选52例慢性阻塞性肺疾病患者,同期入选39例正常者为对照组,采用双抗体夹心酶联免疫吸附试验法测定入选人群血清白介素-13水平。结果慢性阻塞性肺疾病患者血清白介素-13水平显著高于对照组(P<0.05)。慢性阻塞性肺疾病急性加重期患者血清白介素13水平明显高于稳定期(P<0.05)。两亚组与正常组比较均显著高于对照组(P<0.05)。结论慢性阻塞性肺疾病患者血清白介素-13水平明显增高,且急性期高于稳定期;白介素-13可能参与了慢性阻塞性肺疾病的炎症形成过程,与气道高反应性有关。
出处 《中国实用医药》 2009年第5期90-91,共2页 China Practical Medicine
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