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肝移植术后发生糖尿病危险因素、严重程度及处理措施初步探讨

Risk factors and treatment of diabetes mellitus following orthotopic liver transplantation
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摘要 目的探讨肝移植术后发生糖尿病的危险因素及处理方法。方法回顾分析肝移植患者268例术前及术后的临床资料及诊治情况。结果术后糖尿病发生率为25.7%(69/268),发病时间为术后3个月内,均予胰岛素治疗,29例经胰岛素治疗效果不佳者改用环孢A,血糖均有不同程度的控制。结论术后糖尿病是肝移植术后一种高发的代谢并发症,FKS06的应用与PTDM的发生有密切的关系。 Objective To study the risk factors and treatment of post transplantation diabetes mellitus (PTDM) following orthotopic liver transplantation (OLT). Methods Sixty - nine cases of 268 patients who had undergone orthotopic liver transplantation from 2004 to 2008 were retrospectively analyzed. Results The incidence of PTDM was 25.7% (69/268) which was diagnosed in 3 months postoperatively. The blood sugar level of all of the 69 patients were controlled by insulin therapy. Among these patients, 29 patients who were not controlled effectively by insulin could be controlled effectively through changing FK506 into CsA. Conclusions The usage of FK506 is significantly related to the incidence of PTDM.
出处 《武警医学》 CAS 2009年第7期617-618,共2页 Medical Journal of the Chinese People's Armed Police Force
关键词 肝移植 糖尿病 Liver transplantation Diabetes mellitus
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参考文献11

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