摘要
目的研究老年2型糖尿病及合并血管并发症患者C反应蛋白(CRP)和游离脂肪酸(FFA)的变化及相关性,探讨C反应蛋白和游离脂肪酸在老年糖尿病合并血管并发症发生中的作用。方法检测2型糖尿病伴血管并发症组102例,无血管并发症组142例,正常对照组62例血清C反应蛋白与游离脂肪酸水平,分析其差异与相关性。结果伴血管并发症组和无血管并发症组的血清CRP、FFA与正常对照组比较均差异显著(P<0.05)。伴血管并发症组CRP与FFA呈正相关,相关系数r=0.582(P<0.05);FFA和CRP基本无关,相关系数分别为r=0.126和r=0.198(P>0.05)。结论老年2型糖尿病伴血管并发症患者血清中CRP和FFA浓度升高,且高于无血管并发症患者,CRP与FFA水平更具有一致性,血清CRP与FFA检查可用于监测老年2型糖尿病有无血管并发症。
Objective To investigate C -reactive proteins（CRP） and free fatty acids（FFA） levels in the elderly type 2 diabetic patients with complicated angiopathy,and explain their clinical significance. Methods The CRP and FFA were detected in 102 elderly type 2 diabetic patients with angiopathy, 142 without and 62 healthy subjects. Results Both CRP and FFA concentrations in the diabetic patients were significantly higher than those in healthy subjects （P 〈 0.05）, and those in diabetic patients with angiopathy were also significantly higher than those in diabetic patients without angiopathy （P 〈 0.05 ）. CRP was positively correlated with FFA in diabetic patients with angiopathy. Conclusions Both CRP and FFA are increased in the elderly 2 type diabetic patients espcially with angiopathy and they may provide a novel diagnostic and reseach tool for the elderly 2 type diabetic patients with complicated angiopathy.
出处
《武警医学》
CAS
2009年第7期607-609,共3页
Medical Journal of the Chinese People's Armed Police Force
关键词
老年2型糖尿病
血管并发症
CRP
FFA
Elderly type 2 diabetes mellitus Angiopathy C - reactive protein Free fatty acids
