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难治性感染性休克中应用特利加压素的护理 被引量:5

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摘要 目的探讨难治性感染性休克中应用特利加压素(Terlipressin,商品名可利新)的护理措施。方法2006年10月至2008年2月,本院临床诊断为感染性休克病例16例,使用多巴胺和去甲肾上腺素血压仍无法维持[多巴胺剂量超过15μg/(kg.min),去甲肾上腺素剂量超过5μg/min]的情况下加用了特利加压素。结果经过特利加压素使用6h后,16例患者平均动脉压及休克指数与使用前差异均有显著性(P<0.05);HR、尿量经6h治疗后变化差异无显著性(P>0.05),经12h及24h后差异均有非常显著性(P<0.01)。12例患者血压基本稳定,8例在加用利特加压素后72h撤离了去甲肾上腺素,6例患者因多脏器功能衰竭而死亡,病死率37.5%。结论难治性休克患者应用利特加压素可提高抢救成功率,减少其他升压药物用量。
作者 张英
出处 《中国实用医药》 2009年第6期197-198,共2页 China Practical Medicine
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  • 1Martin Westphal,Henning Stubbe,Andreas Sielenk?mper,Reka Borgulya,Hugo Van Aken,Christian Ball,Hans-Georg Bone. Terlipressin dose response in healthy and endotoxemic sheep: impact on cardiopulmonary performance and global oxygen transport[J] 2003,Intensive Care Medicine(2):301~308

同被引文献48

  • 1郑永科,刘长文,朱克毅,陆俊,胡炜.特利加压素在脓毒血症难治性休克中的应用价值[J].浙江临床医学,2007,9(4):455-456. 被引量:7
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