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彩色多普勒超声对复方樟柳碱治疗缺血性眼病的循环改善的评估

Using color Doppler ultrasound to evaluate the treatment effect of compound aniso-dine for the circulatory amelioration of ischemic ophthalmopathy
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摘要 目的:利用彩色多普勒超声评估复方樟柳碱对缺血性眼病循环改善的作用。方法:缺血性眼病患者40例,随机分为治疗组24例,对照组16例,治疗组用北京紫竹药业公司生产的复方樟柳碱注射液2mL患侧颞浅动脉旁皮下注射,1次/d,14次为1个疗程,治疗2个疗程,用彩色多普勒超声检测两组的眼动脉、视网膜中央动脉的收缩期血流峰值速度(peak systolic velocity,PSV),舒张末期血流速度(end-diastolic velocity,EDV),血管内径,阻力指数(resistivity index,RI)。结果:治疗组的PSV,EDV增高,RI下降,血管内径无变化。结论:复方樟柳碱是一种治疗各类缺血性眼病的安全、有效的药物;彩色多普勒超声检测能为其疗效提供一种新的评价方式。 AIM: To evaluate the treatment effect of compound anisodine for the circulatory amelioration of ischemic ophthalmopathy with color Doppler ultrasound. METHODS: Forty patients with ischemic ophthal- mopathy were divided into two groups, the cure group had 24 patients, the control group had 16 patients. The patients of cure group were injected compound anisodine produced from Beijing Zizhu Pharmaceutical co., Ltd subcutaneconsly around superficial temporal artery, once a day, followed up for 28 days, finally, we measured peak systolic velocity ( PSV), end-diastolic velocity ( EDV), resistivity index (RI) and blood vessel diameter of eye artery and central retinal artery of two groups with color Doppler ultrasound. RESULTS: PSV and EDV of the cure group further increased and RI further decreased, the blood vessel diameter didn't ameliorate. CONCLUSION: Compound anisodine injection was safe and effective for the treatment of all kinds of ischemic ophthalmopathy; color Doppler ultrasound is a new way to evaluate the treatment effect of compound anisodine for the circulatory amelioration of ischemic ophthalmopathy.
出处 《国际眼科杂志》 CAS 2009年第7期1406-1407,共2页 International Eye Science
关键词 彩色多普勒超声 复方樟柳碱 缺血性眼病 color Doppler ultrasound compound anisodine ischemic ophthalmopathy
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