摘要
目的探讨内脏大神经切断术治疗胰腺癌晚期疼痛的临床疗效。方法回顾性分析2005年1月至2008年2月行手术治疗的27例胰腺癌晚期患者的临床资料。患者术前均有不同程度的腹痛和，或腰背部痛，其中治疗组16例患者在处理原发病的同时，行左侧内脏大神经切断术，对照组11例仅对原发病进行处理。结果术后3、6个月为随访时限，采用视觉模拟评分法（VAS）进行疼痛评分。治疗组术前VAS评分（6．06±1．93）分，术后3、6个月VAS评分分别为（2．67±1．68）、（2．69±1．75）分，与术前比较差异均有统计学意义（P〈0．01）。对照组术前VAS评分（5．91±1．87）分，术后3、6个月VAS评分分别为（5．11±2．03）、（5．33±2．25）分，差异均无统计学意义。术后3、6个月组间比较，差异有统计学意义（P〈0．05）。治疗组术中均无副损伤，术后均未出现严重消化系统功能紊乱等并发症。结论对于需要处理原发病的胰腺癌晚期患者，左侧内脏大神经切断术操作简单，并发症少，缓解疼痛疗效确切，值得推广。
Objective To investigate the clinical effect of splanchnicectomy for pain palliation with advanced pancreatic carcinoma. Methods Altogether 27 cases were treated from January 2005 to February 2008, retrospective study was used to analyze the clinical data of them. All the patients had diverse extent pain, among these 16 cases who had underwent splanchnicectomy （therapy group）,others were in control group. Results Pain extent was scored according to visual analogue scale （VAS）, preoperative score of therapy group （6.06±1.93） scores, postoperative score 3 months（2.67±1.68） scores, 6 months（2.69±1.75） scores, the discrepancy had statistical significance （P 〈 0.01 ）, preoperative score of control group （5.91±1.87） scores, postoperative score 3 months（5.11±2.03） scores, 6 months（5.33±2.25） scores, the discrepancy had no statistical significance. Intergroups contrast, showing significant difference （P 〈 0.05）. Conclusion For the patients who request to deal with primary disease, splanchnicectomy is manipulated easy, short of complication, significantly relief of pain, and deserve to be spreaded.
出处
《中国医师进修杂志（外科版）》
2009年第7期28-30,共3页
Chinese Journal of Postgraduates of Medicine
