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急诊376例心房颤动患者临床分析

Risk factors and therapeutic effects of atrial fibrillation patients in emergency department analysis of 376 cases
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摘要 目的了解急诊心房纤颤患者病因、房颤类型、抗凝和抗血小板治疗情况,为急诊房颤规范治疗提供依据。方法回顾分析376例以房颤为首诊或其他急症合并有心房纤颤的急诊患者(男203例,女173例,年龄25—86岁)的临床资料,分析病因和房颤类型的构成比、抗凝治疗状况及脑卒中发生情况。结果376例急诊房颤患者主要病因依次为冠心病(41.7%)、高血压(27.4%)和糖尿病(25.2%);患缺血性脑卒中者为91例,占24.2%。与非脑卒中组患者相比,伴缺血性脑卒中的急诊房颤患者年龄偏高(Х^2=16.940,P〈0.001);伴冠心病(Х^2=11.216,P〈0.001),高血压(Х^2=8.195,P=0.004)和糖尿病(Х^2=4.426,P=-0.029)的患者比例也显著较高。抗凝(6.64%)和抗血小板(39.6%)治疗率低,比较脑卒中组和非卒中组抗凝和抗血小板治疗率无显著性差异(P〉0.05)。结论80岁以下的患者中,心房纤颤的发生率随着年龄的增长而增高。年龄、冠心病、高血压和糖尿病为房颤患者脑卒中的主要危险因素。缺血性脑卒中与抗凝治疗效果有关。 Objective To analyze the risk factors, and curative effects of anticoagnlation and antiplatelet treatment of atrial fibrillation (AF) in patients visiting department of emergency. Methods The clinical data of 376 patients with AF who visited department of emergency, 203 males and 173 females, aged 25-86, were analyzed. Results The main underlying diseases of the 376 AF patients included coronary heart disease (41.7%), hypertension (27.4%), and diabetes (25.2%). Ninety-one patients suffered from stroke (24.2%). Compared with the AF patients without cerebral apoplexy, the age of the AF patients with apoplexy, and the ratios with complicated coronary disease, hypertension, and diabetes were all significantly higher (all P〈O.05). The ratios of anti-coagulation treatment and anti-platelet treatment were low, and there were not significant differences in these 2 ratios between the group of cerebral apoplexy and the group of noncerebral apoplexy (both P〉 0.05). Conclusion In the patients under 80, the prevalence rate of AF increases along with the age. Age, coronary heart disease, hypertension, and diabetes are all main risk factors of cerebral apoplexy among the AF patients. Cerebral apoplexy is concerned to the effect of anti-cougnlation.
出处 《中国急救复苏与灾害医学杂志》 2009年第7期475-477,共3页 China Journal of Emergency Resuscitation and Disaster Medicine
关键词 心房颤动 危险因素 脑卒中 Atrial fibrillation Cerebral apoplexy Risk factor
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参考文献12

  • 1周自强,胡大一,陈捷,张仁汉,李奎宝,赵秀丽.中国心房颤动现状的流行病学研究[J].中华内科杂志,2004,43(7):491-494. 被引量:1408
  • 2Wolf PAS, Mitchell JB, Baker CS. et al. Impact of atrial fibrillation on mortality, stroke, and medical costs. Arch Intern Med, 1995, 158: 229-234.
  • 3张文武.急诊内科学[M].北京:人民卫生出版社,2004.166.
  • 4Copper NS, Sutton AJ, Lu K, et al. Mixed comparison of stroke prevention treatments in individuals with nonrheumatie atrial fibrillation. Arch Intern Med, 2006, 12: 1269-1275.
  • 5Fuster V, Ryden LE, Asinger RW, et al. ACC/AHA/ESC guidelines, 2001,104 (17): 2118-2150.
  • 6无.中国脑血管病防治指南(节选)[J].中国现代神经疾病杂志,2006,6(6):432-432. 被引量:29
  • 7Singer DE, Albers GW, Dalen JE, et al. Antithrombotic therapy in atrial fibrillation The 7th ACCP Conference on Antithrombotic and Thrombolitic Therapy. Chest, 2004, 126: 429-456.
  • 8Van Walraven C, Hart RC, Singer DE, et al. Oral anticoagulants vs. aspirin in nonvalvular atrial fibrillation- an individual patient meta-analysis. JAMA, 2002, 288: 2441-2448.
  • 9Lip GYH, Hart RG, Conwary DSC. Antithrombotic therapy for atrial fibrillation. BMJ,2002, 325:1022-1025.
  • 10Ono A, Fujita T. Stroke prevention in patients with atrial fibrillation. J Clin Neurosci, 2003, 10:71-73.

二级参考文献10

  • 1Ouyang F,Ernst S,Chun J,et al.Electrophysiological findings during ablation of persistent atrial fibrillation with electroanatomic mapping and double Lasso catheter technique.Circulation,2005,112:3038-3048.
  • 2Earley MJ,Abrams DJ,Staniforth AD,et al.Catheter ablation of permanent atrial fibrillation:medium term results.Heart,2006,92:233-238.
  • 3Haissaguerre M,Hocini M,Sanders P,et al.Catheter ablation of long-lasting persistent atrial fibrillation:clinical outcome and mechanisms of subsequent arrhythmias.J Cardiovasc Electrophysiol,2005,16:1138-1147.
  • 4Wazni OM,Marrouche NF,Martin DO,et al.Radiofrequency ablation vs antiarrhythmic drugs as first-line treatment of symptomatic atrial fibrillation:a randomized trial.Jama,2005,293:2634-2640.
  • 5Stabile G,Bertaglia E,Senatore G,et al.Catheter ablation treatment in patients with drug-refractory atrial fibrillation:a prospective,multi-centre,randomized,controlled study (Catheter Ablation For The Cure Of Atrial Fibrillation Study).Eur Heart J,2006,27:216-221.
  • 6Oral H,Pappone C,Chugh A,et al.Circumferential pulmonary-vein ablation for chronic atrial fibrillation.N Engl J Med,2006,354:934-941.
  • 7Hsu LF,Jais P,Sanders P,et al.Catheter ablation for atrial fibrillation in congestive heart failure.N Engl J Med,2004,351:2373-2383.
  • 8Pappone C,Rosanio S,Augello G,et al.Mortality,morbidity,and quality of life after circumferential pulmonary vein ablation for atrial fibrillation:outcomes from a controlled nonrandomized long-term study.J Am Coll Cardiol,2003,42:185-197.
  • 9Fuster V,Ryden LE,Cannom DS,et al.ACC/AHA/ESC revision of the 2001 guidelines for the management of patients with atrial fibrillation.Circulation,2006,April (in press).
  • 10胡大一,孙艺红,周自强,李奎宝,倪永斌,杨光,孙淑红,李蕾.中国人非瓣膜性心房颤动脑卒中危险因素的病例-对照研究[J].中华内科杂志,2003,42(3):157-161. 被引量:363

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