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西妥昔单抗联合FOLFOX4方案在转移性结直肠癌一线治疗的疗效预测 被引量：4

Prediction for Cetuximab Combination with FOLFOX4 Regimen in the First-Line Treatment of Metastatic Colorectal Cancer
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摘要 1 文献来源 Bokemeyer C, Bondarenko I, Makhon A, et al. Fluorouracil, Leucovorin, and Oxaliplatin with and without Cetuximab in the first-line treatment of metastatic colorectal cancer [J]. J Clin Oncol,2009,27（5）：663-671.
作者 马冬 董秋美
机构地区 广东省人民医院肿瘤中心
出处 《循证医学》 CSCD 2009年第3期152-154,157,共4页 The Journal of Evidence-Based Medicine
关键词 结直肠肿瘤 西妥昔单抗 FOLFOX4 KRAS colorectal neoplasms Cetuximab FOLFOX4 KRAS
分类号 R735.3 [医药卫生—肿瘤]
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参考文献11

  • 1Jonker DJ,O'Callaghan CJ,Karapetis CS,et al.Cetuximab for the treatment of colorectal cancer[J].N Engl J Med,2007,357(20):2040-2048.
  • 2Cunningham D,Humbler Y,Siena S,et al.Cetuximab monotherapy and Cetuximab plus Irinotecan in Irinotecanrefractory metastatic colorectal cancer[J].N Engl J Med,2004,351(4):337-345.
  • 3Saltz LB,Meropol NJ,Loehrer PJ Sr,et al.Phase Ⅱ trial of Cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor[J].J Clin Oncol,2004,22(7):1201-1208.
  • 4Tabernero J,van Custem E,Diaz-Rubio E,et al.Phase Ⅱ trial of Cetuximab in combination with Fluorouracil,Leucovorin and Oxaliplatin in the first-line treatment of metastatic colorectal cancer[J].J Clin Oncol,2007(25):5225-5232.
  • 5de Roock W,Piessevaux H,de Schutter J,et al.K-RAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with Cetuximab[J].Ann Oncol,2008(19):508-515.
  • 6van Cutsem E,Lang I,D'haens G,et al.KRAS status and efficacy in the first-line treatment of patients with metastaic colorectal cancer (mCRC) treated with FOLFIRI with or without Cetuximab:The CRYSTAL experience[J].J Clin Oncol,2008(26,5s):abstr 2.
  • 7Amado RG,Wolf M,Peeters M,et al.Wild-type K-RAS is required for panitumumab efficacy in patients with metastatic colorectal cancer[J].J Clin Oncol,2008(26):1626-1634.Tol J,Koopman M,Cats A,et al.Chemotherapy,.
  • 8Bevacizumab,and Cetuximab in metastatic colorectal cancer[J].N Engl J Med,2009,360(6):563-572.Nicolantonio FD,Martini M,Molinari F,et al.Wild-type.
  • 9BRAF is required for response to Panitumumab or Cetuximab in metastatic colorectal cancer[J].J Clin Oncol,2008(26):5705-5712.Jhawer M,Goel S,Wilson AJ,et al.PIK3CA mutation/PTEN.
  • 10expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor Cetuximab[J].Cancer Res,2008,68(6):1953-1961.Sartore-Bianchi A,Martini M,Molinari F,et al.PIK3CA.

同被引文献26

引证文献4

二级引证文献22

循证医学
2009年 第3期

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