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依托咪酯镇静时不同年龄患者脑电双频指数与镇静评分之间的相关性因素分析 被引量:14

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摘要 目的观察使用依托咪酯镇静时年龄对脑电双频指数(BIS)和镇静/警醒评分(OAA/S评分)之间的相关性有无影响。方法150例未用术前药的患者,按年龄分为青年组(18~39岁)、中年组(40~64岁)和老年组(65-80岁),每组再分为给予依托咪酯0.068、0.085、0.106、0.131和0.166mg/kg5个剂量组,每个剂量组10例。记录5min BIS和OAA/S评分等指标,并对年龄与BIS和0AA/s评分进行相关性分析。结果随年龄增长,BIS值显著升高;OAA/S评分1分或2分(深度镇静)时老年组BIS值显著高于青年组(P均〈0.05);BIS值与OAA/S评分呈正相关,r老年组=0.72,r中年组=0.79,r青年=0.76,P均〈0.05;依托咪酯的剂量与BIS值呈负相关,r老年组=0.59,r中年组=0.41,r青年=0.45,P均〈0.05。结论给予镇静剂量的依托咪酯,BIS随着年龄增加呈递增趋势。
出处 《中国危重病急救医学》 CAS CSCD 北大核心 2009年第7期442-443,共2页 Chinese Critical Care Medicine
基金 四川省成都市科技攻关项目(成科计[2007]1号)
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