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D2-40标记的淋巴管侵犯在非小细胞肺癌中的预后价值 被引量：5

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摘要 目的:在较准确判断肿瘤内淋巴管侵犯的基础上,探讨淋巴管侵犯在非小细胞肺癌中的预后价值。方法:应用D2-40单克隆抗体标记53例行根治性手术的Ⅰ～ⅢA期非小细胞肺癌组织的淋巴管内皮细胞,检查淋巴管侵犯发生的情况及淋巴管侵犯与淋巴结转移、无瘤生存期的关系。结果:LVI发生率在N0、N1、N2组分别为21.4%(6/28)、44.4%(4/9)、68.8%(11/16),差异有统计学意义(P=0.002)。多因素分析结果显示LVI为无区域淋巴结转移的早期非小细胞肺癌(T1～3N0M0期)的不良预后因素。结论:LVI与非小细胞肺癌淋巴结转移相关,是无区域淋巴结转移的早期非小细胞肺癌的独立不良预后因素。
作者 冯卫能 谷力加 邓燕明 刘勇 郭少忠 王巍 张顺达
机构地区 广东省佛山市第一人民医院肿瘤医院肿瘤内科 中山大学附属第三医院胸心外科 中山大学附属第三医院病理科
出处 《实用医学杂志》 CAS 北大核心 2009年第14期2295-2297,共3页 The Journal of Practical Medicine
关键词 癌 非小细胞肺 淋巴管侵犯 D2-40
分类号 R734.2 [医药卫生—肿瘤] R735.2 [医药卫生—肿瘤]
  • 相关文献

参考文献10

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二级参考文献10

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共引文献4

同被引文献48

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引证文献5

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实用医学杂志
2009年 第14期

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