摘要
文章研究良恶性梗阻性黄疸（梗黄）胆汁、血清免疫球蛋白（Ig）和补体（C）水平的变化。研究分4组：对照组（A组，n＝10），非黄疸性胆道结石组（B组，n＝12），良性梗黄组（C组，n＝14）和恶性梗黄组（D组，n＝7）。结果显示：（1）和A组比较，C组血清IgM和D组血清C3升高（P＜0．05）；（2）和B组比较，C组胆汁C3升高（P＜0．05），和B、C组比较，D组胆汁IgM、C3和C4下降（P＜0．05～0．001）。结果提示：恶性梗黄胆道体液免疫功能和补体经典途经功能均明显下降。
Immunoglobulin(Ig )and complement(C)levels in bile and serum were analyzed in patients with benign and malignant jaundice. 43 subjects were divided into 4 groups: group A (control, n=10), group B (cholelithiasis without jaundice, n=12 ),group C(benign jaundice,n=14)and group D(malignant jaundice,n=7). The result showed that: (1)Serum IgM level in group Cand serum C3 level in group D were higher than those in group A(P<O. 05);(2)Bile C3 level in group C were higher than that ingroup B (P<0. 05). And bile IgM,C3 and C4 levels in group D were lower than those in group B and C(P<0. 05~0. 001). The result indicated significantly the decrease in biliary humoral immunity and defect in biliary classical complement pathway in patientswith malignant jaundice.
出处
《肝胆外科杂志》
1998年第3期185-186,共2页
Journal of Hepatobiliary Surgery
关键词
胆道梗阻
胆汁
免疫球蛋白
补体
Bile duct obstruction Bile Immunoglobulin Complement
