摘要
目的探讨布地奈德、沙丁胺醇加异丙托溴铵雾化吸入治疗毛细支气管炎的疗效。方法104例毛细支气管炎患儿分为治疗组和对照组,在相同的综合治疗基础上,对照组仅常规使用激素,治疗组则用雾化吸入,每次用布地奈德悬液1～2ml(布地奈德0.5～1mg,阿斯利康公司);异丙托溴铵悬液0.5ml(异丙托溴铵125μg,勃林格殷格翰国际有限公司);沙丁胺醇液0.03ml/kg(沙丁胺醇0.15mg/kg,葛兰素史克公司),加生理盐水至2ml,每天2-3次,疗程3～5d。结果治疗组治愈38例(73.1%),好转11例(21.2%),无效3例(5.8%),总有效率94.3%。对照组治愈21例(40.4%),好转16例(30.8%),无效15例(28.8%),总有效率71.2%,两组比较差异具显著性(P<0.05)。结论布地奈德、沙丁胺醇加异丙托溴铵雾化吸入治疗毛细支管炎方法简单、起效快、患儿耐受性好、疗效确切。
Objectives ： To detect the efficacy of Budesonide. Salbutamol and Ipratropium Bromide nebulizing inhaled treat bronchiolitis. Methods ： 104cases of bronchiolitis divide into treatment group and control group. On the basis of the same general treatment, the control group regularly use glucocorticosteroid, the treatment group use nebulizing inhaled associated drugs： Budesonide liguid 1 - 2 ml per time （Budesonide 0. 5 - 1 mg AstraZeneca company ） , Ipratropium Bromide liquid 0. 5ml （Ipratropium 125μg, Boehringer Ingelheim company ）, Salbutamol 0. 03 mg/kg （Salbutamol 0. 15mg/kg, Glaxo Smithkline company）, plus NS to 2ml, 2 -3 times daily, treatment process 3 -5 days. Results： The treatment group： cure 38 cases （73.1%）, better 11 cases （21.2%）, null and void 3 case （5.8%）, general efficiency 94. 3% , the control group cure 21 cases （40.4%）, better 16 cases （30. 8% ）, null and void 15 case （28.8%）, general efficiency 71.2%. compare the treatment group with the control group was significant difference （ P 〈 0. 05 ）. Conclusions： Budesonide. Salbutamol and Ipratropium Bromide nebulizing inhaled treat bronchiolitis, The method is single, pruducting efficacy is rapid, children＇s tolerance is good and the treatment efficiency is certainty.
出处
《中国优生与遗传杂志》
2009年第7期124-125,74,共3页
Chinese Journal of Birth Health & Heredity
