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水通道蛋白4的研究进展 被引量:7

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摘要 AQP家族是近几年来逐渐被发现并认识的一类水特异性膜内在蛋白,已有200多种水通道广泛分布于动物植物微生物中,在哺乳动物组织中已发现13种水通道蛋白(AQP0-AQP12)。迄今已在脑内已发现7种AQP,别是AQP1,3,4,5,8,9,11,其中水通道蛋白-4(AQP4)为主要在脑组织中表达的水通道蛋白。它参与了脑缺血、脑水肿等病理生理过程,调节水通道蛋白表达水平可能为脑缺血、脑水肿等的治疗提供新的途径。
出处 《中国实用医药》 2009年第20期238-241,共4页 China Practical Medicine
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