摘要
以ＣＣ１４等因素复制大鼠肝纤维化模型，以血清丙氨酸氨基转移酶（ＡＬＴ）水平，血清层粘连蛋白（ＬＮ）、透明质酸（ＨＡ）含量，光、电镜下肝组织改变为观察内容，观察荣肝饮的治疗作用，设正常组和模型组作为对照。结果表明，荣肝饮能显著降低血清ＡＬＴ水平及血清ＬＮ、ＨＡ含量，明显改善肝组织炎症状态，与模型组比较，Ｐ＜０．０１。表明荣肝饮有一定的抗肝纤维化的作用。
We duplicated the animal pattern of the liver fibrosis by injecting CCl_4 suspension to white Mice's abbominal cavity,and take the content of ALT、HA、LN in blood serums and the change of the hepatic tissue under the optical and the electron microscope.After 4 weeks treatment with Rongan decoction,compared with the control group,the liver function and the serum parameters of fibrosis were significantly decreased(p<0.01)。The results show that Ronggan decoction has the effect of antifibrosis,and the further improved study is needed.
出处
《山东中医药大学学报》
1998年第4期309-310,共2页
Journal of Shandong University of Traditional Chinese Medicine
关键词
荣肝饮
肝纤维化
中医药疗法
Ronggan decoction Liver fibrosis ALT Laminin HyaluronicacidHepatic tissue White Mice
