摘要
目的探讨经肛门内镜显微手术（TEM）在治疗局限性直肠肿瘤中的应用效果。方法总结分析2006年4月至2008年12月接受TEM的75例直肠肿瘤患者的临床资料，分析TEM在直肠肿瘤治疗中的应用效果。结果患者病灶平均直径为（1．6±0．8）cm（0．5～5．0cm）。病灶距肛缘平均（7．6±2．8）cm（5～20cm）。病灶在直肠内的部位：前壁25例，后壁24例，左侧壁14例，右侧壁12例。手术方式包括：肠壁全层切除64例，黏膜下及肌层部分切除11例。平均手术时间（73．7±32．1）min（30～180min），术中平均失血（9．8±7．7）ml（3～50m1）。术后病理检查：直肠腺瘤28例，直肠腺瘤癌变和直肠癌25例（其中Tis期14例，T1期5例，他期6例），直肠类癌7例，炎性息肉等15例。所有标本切缘均为阴性。全组术后4例（5．3％）发生并发症，其中并发肛门出血2例，肺部和泌尿系感染各1例。术后平均住院（3．4±1．2）d（2～7d）。术后平均随访8．4个月（3～26个月），未发现疾病或肿瘤有复发转移。结论TEM治疗直肠肿瘤具有手术损伤小，出血少、疗效好、恢复快等优点，是目前直肠肿瘤局部切除的较佳方法。
Objective To investigate the therapeutic effect of transanal endoscopic microsurgery （TEM） for localized rectal neoplasms. Methods Seventy-five patients with localized rectal neoplasms were treated by using TEM between April 2006 and December 2008. The clinical data was summarized and analyzed retrospectively to report the therapeutic effect of TEM in these cases. Results The mean diameter of the rectal lesions was （ 1.6 ±0. 8 ） cm （ range, 0. 5-5.0 cm）. The average distance of lesions from the anal verge was （7.6±2.8） cm （range, 5-20 cm）. Locations of the lesions at the rectal wall： 25 located at the anterior wall, 24 at the posterior wall, 14 at the left wall and 12 at the right wall. Surgical procedures included the transmural excision （64 cases） and the submucosal excision with partial muscular layer excision （11 cases） was performed. The average operating time was （73.7±32. 1 ） min （range, 30-180 min）. The mean operative blood loss was （ 9. 8±7.7 ） ml （ range, 3-50 ml ） . The postoperative pathological examination identified 28 cases of rectal adenoma, 25 rectal adenocarcinoma or carcinomatous changes of adenoma （14 cases with phase Tis tumor, 5 cases T1 and 6 cases T2） , 7 rectal carcinoid and 15 cases of inflammatory polyps or others. Surgical margins of all specimens were negative. Postoperative complications occurred in 4 cases （5.3%）, included 2 cases of anal hemorrhage, 1 case of pulmonary infection and 1 urinary infection. The average postoperative hospital stay was （ 3.4±1.2） d （ range, 2-7 d）. All the patients were followed-up for a mean period of 8.4 months （ range, 3-26 months）, no tumor recurrence or metastasis was observed. Conclusion Being a kind of minimally invasive surgery, TEM shows advantages of decreased blood loss, better therapeutic effect and faster recovery, and it is a better choice of procedure for local excision for rectal neoplasms.
出处
《中华外科杂志》
CAS
CSCD
北大核心
2009年第13期981-983,共3页
Chinese Journal of Surgery
关键词
直肠肿瘤
局部切除
经肛门内镜显微手术
Rectal neoplasms
Local excision
Transanal endoscopic microsurger
