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16~22岁新兵毒力型幽门螺杆菌感染的血清流行病学特点

Study on seroprevalence of toxical Helicobacter pylori infection among 16~22 years old recruits
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摘要 目的调查16~22岁新兵中毒力型幽门螺杆菌感染的情况及影响因素,为部队卫生防病工作提供参考依据。方法对某部新兵248人进行一般状况及胃肠疾病等情况的问卷调查,并测定血清中毒力菌株幽门螺杆菌抗体(CagA-HP-IgG)。结果16~22岁新兵中毒力菌株阳性检出率为46.8%,饮用地下水者(感染率43.3%)与饮用河湖/池塘/沟渠水者(感染率59.2%)之间存在差异(P<0.05);不吸烟者(感染率37.2%)与吸烟者(感染率51.1%)之间存在差异(P<0.05);有胃肠道症状者(感染率53.5%)与无胃肠道症状者(感染率37.7%)之间存在差异(P<0.05);有集体生活史者(感染率55.9%)与无集体生活史者(感染率38.8%)之间存在差异(P<0.01)。结论新兵中毒力菌株感染率较高,可能与饮用水源、吸烟、胃肠道症状及集体生活史有关。提示净化水源、控制吸烟、改善居住条件有助于降低部队毒力菌株感染与流行。 Objective To explore toxical Helicobacter pylori (H. pylori) infection for helping diseases prevention in military. Methods Two hundred and forty-eight cases 16 -22 years old recruits were investigated by questionnaire of gastrointestinal symptoms and CagA-HP-IgG antibody was detected. Results The positive rate of toxical H. pylori in recruits was 46.8%. The difference was significant in recruits who drank spring water and river/pool/conduit water (P 〈 0.05), non-smokers and smokers (P 〈 0.05 ), with gastrointestinal symptoms and no gastrointestinal symptoms (P 〈 0.05 ) , with group life history and no group life history (P 〈 0.01 ). Conclusion The incidence of toxical H. pylori infection is higher than common population. And the incidence is different for different group with drinking water source, smoking history, gastrointestinal abnormal symptoms and group living history. It is possible to prevent toxical H. pylori infection by purifying water, controlling smoking and improving living conditions.
出处 《胃肠病学和肝病学杂志》 CAS 2009年第7期652-654,共3页 Chinese Journal of Gastroenterology and Hepatology
关键词 幽门螺杆菌 血清CagA-HP-IgG 流行病学 Helicobacter pylori CagA-HP-IgG Epidemiology
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