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原发性胆汁性肝硬化的动物模型特点与研究进展 被引量:1

The characteristics and progress of primary biliary cirrhosis animal model
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摘要 研究原发性胆汁性肝硬化(primary biliary cirrhosis,PBC)的三种动物模型:非肥胖型糖尿病(NOD c3.c4)小鼠模型、TGFβII型受体显性失活(dn TGFβRII)小鼠模型、IL-2Rα-/-小鼠模型的特点及其意义。 The characteristics and significance of three animal models on primary biliary cirrhosis-non obesity diabetic c3. c4 ( NOD c3. c4) mouse model, dominant-negative TGF-beta receptor type Ⅱ (dn TGFβ RⅡ) mouse model and IL-2 receptor alpha (-/-) mouse model were studied.
出处 《胃肠病学和肝病学杂志》 CAS 2009年第7期584-586,共3页 Chinese Journal of Gastroenterology and Hepatology
关键词 原发性胆汁性肝硬化 动物模型 Primary biliary cirrhosis (PBC) Animal model
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参考文献9

  • 1He XS, Ansari AA, Ridgway WM, et al. New insights to the immunopathology and autoimmune responses in primary biliary cirrhosis [ J]. Cell Immunol, 2006, 239(1): 11-13.
  • 2Tisch R, McDevitt H. Insulin-dependent diabetes mellitus [J]. Cell, 1996, 85(3) : 291-297.
  • 3Koarada S, Wu Y, Fertig N, et al. Genetic control of autoimmunity: protection from diabetes, but spontaneous autoimmune biliary disease in a nonobese diabetic congenic strain [ J]. J Immunol, 2004, 173 (4) : 2315-2323.
  • 4Irie J, Wu Y, Wicker LS, et al. NODc3. c4 congenic mice develop autoimmune biliary disease that serologically and pathogenetieally models human primary biliary cirrhosis [J]. J Exp Med, 2006, 203(5) : 1209-1219.
  • 5Oertelt S, Lian ZX, Cheng CM, et al. Anti-mitochondrial antibodies and primary biliary cirrhosis in TGF-beta receptor Ⅱ dominant-negative mice [J]. J Immunol, 2006, 177(3) : 1655-1660.
  • 6Aoki CA, Roifman CM, Lian ZX, et al. IL-2 receptor alpha deficiency and features of primary biliary cirrhosis [ J]. J Autoimmun, 2006, 27 (1): 50-53.
  • 7Wakabayashi K, Lian ZX, Moritoki Y, et al. IL-2 receptor alpha(√-) mice and the development of primary biliary cirrhosis [ J ]. Hepatology, 2006, 44 ( 5 ) : 1240-1249.
  • 8Kaplan MM, Gershwin ME. Primary biliary cirrhosis [J]. N Engl J Med, 2005, 353: 1261-1273.
  • 9Ueno Y, Moritoki Y, Shimosegawa T, et al. Primary biliary cirrhosis: what we know and what we want to know about human PBC and spontaneous PBC mouse models [ J ]. J Gastroenterol, 2007, 42 (3): 189-195.

同被引文献1

  • 1陈成伟,成军,窦晓光,段维佳,段钟平,范建高,傅青春,高春芳,侯金森,胡和平,胡锡琪,黄建荣,韩涛,韩英,贾继东,陆伦根,刘玉兰,马雄,茅益民,南月敏,牛俊奇,邱德凯,任红,尚佳,唐红,王贵强,王吉耀,王建设,王磊,王宇明,魏来,许建明,徐铭益,谢青,谢渭芬,徐小元,杨长青,杨云生,尤红,曾民德,张文宏,张跃新,周新民,庄辉,邹晓平.原发性胆汁性肝硬化(又名原发性胆汁性胆管炎)诊断和治疗共识(2015)[J].临床肝胆病杂志,2015,31(12):1980-1988. 被引量:188

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