摘要
目的:比较托特罗定联合萘哌地尔与单用托特罗定治疗女性膀胱过度活动症的疗效。方法:将35例女性膀胱过度活动症患者随机分为托特罗定联合萘哌地尔治疗组(18例)与单用托特罗定治疗组(17例),治疗时间为4周,以平均24 h排尿次数、平均24 h尿失禁次数、初始尿意容量(FDV)、最大膀胱压容量(MCBC)、最大尿流率(Qmax)为疗效指标,比较两组疗效。结果:2组间比较治疗前后24 h排尿次数、平均24 h尿失禁次数、初始尿意容量(FDV)、最大膀胱压容量(MCBC)、最大尿流率(Qmax),差异有显著性(P<0.05),联合用药组的上述指标的改善程度明显优于单独用药组。结论:托特罗定联合萘哌地尔治疗女性膀胱过度活动症的疗效优于单用托特罗定。
Objective： To compare the the clinical effect of tolterodine combined with naftopidil and that of tolterodine alone for female overactive bladder （OAB）. Methods： Thirty-five female patients with OAB were randomly divided into tolterodine plus naftopidil treatment group A （group A, n =18） and tolterodine alone treatment group （group B, n=17）. The effects were evaluated with urodynamic data including frequency of micturiation and incontinence, maximum flow rate （Qmax）, first desire to void（FDV）, and maximum cystometric capacity （MCC）. Results： The changes of frequency of micturiation and incontinence, Qmax, FDV, and MCC had significant difference between the two groups （P〈0.05）. Respectively, all the urodynamic data of group A showed significant improvement, compared with those of group B. Conclusion： Tolterodine combined with naftopidil could be an effective method for female overactive bladder.
出处
《武汉大学学报（医学版）》
CAS
北大核心
2009年第4期547-549,共3页
Medical Journal of Wuhan University
