摘要
目的:探讨参麦注射液对大鼠急性缺血再灌注心肌结构的影响。方法:24只大鼠随机分为3组(n=8):假手术组、心肌缺血再灌注模型组和参麦注射液治疗组,各组缺血30min,再灌注2h后取心肌标本,分别在光镜和电镜下观察。结果:与模型组相比,参麦治疗组心肌细胞和细胞器破坏显著减轻,局部出血很少,结构接近正常。结论:参麦注射液对缺血再灌注心肌具有保护作用。
Objective： To investigate the effects of Shenmai injection（SMI） on the structure of acute myocardial ischemia-reperfusion injury（MIRI） in rats. Methods：24 rats were divided randomly into 3 groups（n = 8） ：sham-operated group, myocardial ischemia-reperfusion（MIR） model group and SMI group. The myocardium was observed under light and electronic microscope. Results：Compared with MIR model group, the destruction of myocardial cells and organeltes were attenuated significantly in SMI group. Conclusion.. Shenmai injection can protect the myocardium on myocardial ischemia-reperfusion injury in rats.
出处
《河北北方学院学报（医学版）》
2009年第3期21-23,共3页
Journal of Hebei North University:Medical Edition
基金
河北省科学技术研究与发展指导计划项目(编号:062761366)
关键词
参麦注射液
大鼠
心肌缺血
再灌注损伤
Shenmai Injection,Rats, Myocardial Ischemia,Reperfusion Injury
