期刊文献+

信号转导在肾结石形成机制中的研究进展

原文传递
导出
摘要 细胞信号转导的研究是当前生命科学研究的重要课题,细胞信号转导通路的多样性、复杂性以及细胞内外跨膜过程,都有不同的信息分子和相对应的受体。信号转导的异常,与疾病的发生发展密切相关。本文通过研究肾小管细胞信号转导,了解在信号转导过程中,信号通路的功能改变与肾结石形成的相关性,对于肾结石的防治有重要意义。本文就近来年在信号通路领域的研究与肾结石发生的联系作一综述。
出处 《国际泌尿系统杂志》 2009年第4期536-540,共5页 International Journal of Urology and Nephrology
  • 相关文献

参考文献23

  • 1Han HJ,Lim MJ,Lee YJ.Oxalate inhibits renal proximal tubule cell proliferation via oxidative stress,p38 MAPK/JNK,and cPLA2 signaling pathhways.Am J Physiol Cell Physiol,2004,287(4):C1058 -C1066.
  • 2Obata T,Brown GE,Yaffe MB.MAP kimase pathways activated by stress:The p38 MAPK pethway.Crit Care Med,2000,28(4):67 -77.
  • 3Pearson G,Robinson F,Bners Gibann T,et al.Mitogeu-activated protein(MAP) kinase pathways:Regulation and physiological functions,Endocr Rev,2001,22(2):153-183.
  • 4Kanamoto T,Mots M,Takeda K,et al.Role of apoptesis signal-regulating kinase in regulation of the c-Jun N-terminal kinase pathway and apoptesis in sympathetic neurons.Mol Cell Biol,2000,20 (1):196 -2O4.
  • 5Ono K,Han J.The p38 signal transduction pathway:activation and function.Cell Signal,2000,12(1):1-13.
  • 6Obata T,Brown GE,Yaffe MB.MAP kinase pathways activated by stress:the p38 MAPK pathway.Crit.Care Med,2000,28(s4):67 -77.
  • 7Omori S,Hida M,Ishikura K,et al.Expression of mitogen-activated protein kinase family in rat renal development.Kidney Int.2000,58(1):27 -37.
  • 8Stambe C,Atkins RC,Hill PA,et al.Activation and cellular lncalization of the p38 and JNK MAPK pathways in rat crescentic glomemlonephritis.Kidney Int,2003,64(6):2121 -2132.
  • 9Koul HK,Menon M,Chaturvedi LS,et al.COM crystals activate the p38mitoge-activated protein kinase (MAPK) signal transduet/on pathway in renal epithelial celh.J Biol Chem,2002,277(39):36845-36852.
  • 10Chatorvedi LS,Konl S,Sekhon A.Oxalate selectively activates the p38 mitogen-activated protein kinase and c-Jun N-terminal ki nese signal transduction pathway in renal epithelial cells.J Biol Chem,2002:13321-13330.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部