期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

CD146与前列腺癌的研究进展

原文传递
导出
摘要 前列腺癌是泌尿生殖系中一种常见的肿瘤，其发病较为隐蔽，诊断、治疗比较复杂、困难。近来研究表明黏附分子CD146是一个新的肿瘤血管内皮标志分子，参与前列腺癌的新生血管生成和肿瘤的生成与转移。在前列腺癌细胞中的表达较正常的前列腺上皮细胞高。是一种潜在的早期诊断指标，也将是药物或基因治疗的潜在靶标。本文就CD146在前列腺癌中的研究进展加以综述。
作者 马建华(综述) 白进良(审校) 马鹏程(审校)
机构地区 兰州大学第一医院泌尿外科
出处 《国际泌尿系统杂志》 2009年第4期484-487,共4页 International Journal of Urology and Nephrology
关键词 前列腺肿瘤 抗原 CD14
分类号 R737.25 [医药卫生—肿瘤]
  • 相关文献

参考文献27

  • 1刘玉琴.肿瘤血管形成机理研究进展[J].基础医学与临床,2004,24(3):239-244. 被引量：4
  • 2Sers C,Kirsch K,Rothbacher U,et al.The gene encoding the melanoma-associated glyeoprotein MUC18 displays a unique structure among the members of the immunoglobulin superfamily.Proc Natl Acad Sci U S A,1993,90:8514-8518.
  • 3Shih IM,Speicher D,Hsu MY,et al.Melanoma cell-cell interactions are mediated through heterophilic Mel-CAM/ligand adhesion.Cancer Res,1997,57:3835-3840.
  • 4Satyemoorthy k,muyrers j,meier F,et al.Mel-CAM-specific genetic suppressor elements inhibits melanoma growth and invasion through loss of gap junction communication.Oncogene,2001,20(34):4676 -4684.
  • 5Shih IM.The role of CD146 (mel-cam) in biology and Pathology.J.Pathol,1999,189:4-11.
  • 6Vainio O,Dunon DL,Aissi F,et al.HEMCAM.An adhersion moceule expressed by c -kit hemotopoietic progeniters.J Cell Biol,1996,135:1655-1668.
  • 7Bardin N,Frances V,Lesaule G,et al.Identification of the S-Endo 1 endothelial -associated antigen.Biochem Biophys Res Commun,1996,218 (1):210-216.
  • 8Shih I M,Kurman R J.Expression of melanoma cell adhesion molecule in intennediate trophoblast.Lab Invest,1996,75 (3):377 -388.
  • 9Liu Q,Yan X,Li Y,et al.Pre-eclampsia is associated with the failure of melanoma adhesion molecule (MCAM/CD146) expression by intermediate trophoblast.Lab Invest,2004,84(2):221 -228.
  • 10Filshie R J,Zannettino A C,Makrynikola V,et al.MUC18,a member of the immunogolobulin superfamily,is expressed on bone marrow fibroblasts and a subset of hematological malignancies.Leukemia,1998.12 (3):414 -421.

二级参考文献29

  • 1刘玉琴,顾蓓,王春景,张宏,高进,任民峰.体外肿瘤细胞对血管内皮细胞影响的观察[J].中华病理学杂志,2003,32(4):360-363. 被引量：1
  • 2Marschall Z, Scholz A, Cramer T, et al. Effects of interferon alpha on vascular endothelial growth factor gene transcription and tumor angogenesis[J]. J Natl Cancer Inst, 2003,95(6):437-448.
  • 3Amano H, Hayashi I, Endo H, et al. Ost prostaglandin E(2)-EP3 signaling regulates tumor-associated angiogenesis and tumor growth[J]. J Exp Med, 2003, 197(2):221-232.
  • 4Dixelius J, Cross MJ, Matsumoto T, et al. Endostatin action and intracellular signaling: beta-catenin as a potential target[J]. Cancer Lett, 2003, 196(1):1-12.
  • 5Leali D, Dell'Era P, Stabile H, et al. Osteopontin (Eta-1) and fibroblast growth factor-2 cross-talk in angiogenesis[J]. J Innumol, 2003, 171(2):1085-1093.
  • 6Chadderton NS, Stringer SE. Interaction of platelet factor 4 with fibroblast growth factor 2 is stabilized by heparan sulphate[J]. Int J Biochem Cell Biol, 2003, 35(7):1052-1055.
  • 7Choi KS, Bae MK, Jeong JW, et al. Hypoxia-induce angiogenesis during carcinogenesis[J]. J Biochem MOl Biol, 2003, 36(1):120-127.
  • 8Mabjeesh NJ, Esculin D, LVallee TM, et al.2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF[J]. Cancer Cell, 2003, 3(4):363-375.
  • 9Zhang L, Yang N, Park JW, et al. Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelial and destabilizes host vasculature, supporting angiogenesis in ovarian cancer[J].Cancer REs, 2003,63(12):3403-3412.
  • 10Feoktistov I, Ryzhov S, Goldstein AE, et al. Mast cell-mediated stimulation of angogenesis: cooperative interaction between A2B and A3 adenosine receptors[J]. Circ Tes, 2003,92(5):485-492.

共引文献12

国际泌尿系统杂志
2009年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部