摘要
目的：观察抗精子抗体对精子顶体酶活性的影响。方法：选择男性不育者５０例，与正常生育者２０例。采用固相酶染色法测抗精子抗体，固定明胶薄膜法测精子顶体酶活性。结果：５０例不育者抗精子抗体阳性率为５２％。不育者精子顶体酶活性明显低于生育者；抗精子抗体阳性者顶体酶活性低于阴性者。结论：抗精子抗体可降低精子顶体酶活性。
biect: Study the effect of antisperm antibody on human acrosin. Method: Selected 50 cases of unexplained infertility (52% with sperm antibody) and 20 cases of fertile volunteers, using the fixed gelatin membrane method to detect the acrosin activity. Results: Acrosin activity of infertility was lower than that of fertile cases, and antisperm antibody could significantly reduce human acrosin activity. Conclusion: Antisperm antibody could affect acrosin activity.
